HAT1 and ZSCAN4

Data Source:
BioGRID (two hybrid)

		HAT1	ZSCAN4
Description		histone acetyltransferase 1	zinc finger and SCAN domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Protein-containing Complex	Chromosome, Telomeric Region Nucleus
	Molecular Function	Histone Acetyltransferase Activity Protein Binding H4 Histone Acetyltransferase Activity Histone Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA Packaging DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Chromatin Silencing At Telomere Internal Protein Amino Acid Acetylation Response To Nutrient Histone H4 Acetylation	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Recombination
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		23 interacting genes: ACAA1 H2AC20 H3-4 H3C1 H4-16 H4C1 H4C14 HTR2B KANK4 MEOX2 MORN5 PRKAA2 RBBP4 REL SMAD7 SNAPC1 STEEP1 TCF4 TEPSIN TNFAIP1 TRIB3 YWHAQ ZSCAN4	13 interacting genes: CIB3 CTBP2 EXOC8 FAM110A HAT1 HCK KAT5 LAMTOR3 PARD6B SMAD1 SMAD9 TBC1D22B TRAF3
Entrez ID		8520	201516
HPRD ID		04339	15899
Ensembl ID		ENSG00000128708	ENSG00000180532
Uniprot IDs		O14929	Q8NAM6
PDB IDs		2P0W 6VO5
Enriched GO Terms of Interacting Partners?
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