SF1 and ZNF461

Data Source:
BioGRID (pull down, pull down)

		SF1	ZNF461
Description		splicing factor 1	zinc finger protein 461
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome	Nucleus
	Molecular Function	Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription, DNA-templated Regulation Of MRNA Splicing, Via Spliceosome	Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway	Generic Transcription Pathway
Drugs		Artenimol
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Urate levels ( 21768215)
Interacting Genes		58 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CDC42 CIAO1 DDX17 DUX4L9 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MIR106B MIR155 MIR19B2 MIR34A MIRLET7G MKRN3 NCK2 NFKB1 OSTF1 PLSCR1 PRKG1 PRPF40A PSMA3 PUF60 RBM10 RBM17 RBM4 RBM7 RBPMS SEC23A SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TNPO2 TRIM23 TRIM69 TTN TXNL4B U2AF2 UBL5 WBP4 WDR77 WDR83 WWP2 ZNF461	5 interacting genes: HDAC2 KRTAP10-3 MDFI SF1 TOX2
Entrez ID		7536	92283
HPRD ID		03306	16358
Ensembl ID		ENSG00000168066	ENSG00000197808
Uniprot IDs		A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637	B4DRP8 Q8TAF7
PDB IDs		1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX
Enriched GO Terms of Interacting Partners?
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