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UBASH3B and LZTS2
Data Source:
BioGRID
(two hybrid)
UBASH3B
LZTS2
Description
ubiquitin associated and SH3 domain containing B
leucine zipper tumor suppressor 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cytosol
Microtubule
Plasma Membrane
Midbody
Vesicle
Molecular Function
Protein Tyrosine Phosphatase Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Phosphoprotein Binding
Protein Binding
Biological Process
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Signal Transduction
Peptidyl-tyrosine Dephosphorylation
Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Regulation Of Protein Binding
Regulation Of Osteoclast Differentiation
Negative Regulation Of Osteoclast Differentiation
Negative Regulation Of Bone Resorption
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Platelet Aggregation
Negative Regulation Of Platelet Aggregation
Mitotic Cytokinesis
Negative Regulation Of Cell Population Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Primary Ureteric Bud Growth
Ureter Morphogenesis
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Blood protein levels (
30072576
)
Blood urea nitrogen levels (
31152163
)
Cholesterol, total (
24097068
25961943
20686565
)
Chronotype (
30696823
)
Diastolic blood pressure (
30224653
)
Eye length (
30174134
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
HDL cholesterol (
24097068
20686565
)
HDL cholesterol levels (
32203549
)
High light scatter reticulocyte percentage of red cells (
32888494
)
LDL cholesterol levels (
32203549
)
Low density lipoprotein cholesterol levels (
32154731
)
Multiple sclerosis and HDL levels (pleiotropy) (
26920376
)
Pemphigus vulgaris (
29857070
)
Serum immune biomarker levels (
32066700
)
Stroke (
26089329
)
Systolic blood pressure (
30578418
)
Total cholesterol levels (
28334899
)
Ejection fraction in Tripanosoma cruzi seropositivity (
24324551
)
Regular attendance at a pub or social club (
29970889
)
Interacting Genes
51 interacting genes:
BBC3
CBL
CBLB
CCDC74B
CUL3
DAZAP2
DISC1
DLGAP2
DMRT3
DOC2A
DTX3
EFS
FAM168A
HOXB2
INCA1
JAK2
KAT5
KDM1A
KHDRBS1
KPRP
LMO2
LZTS2
MAP3K1
PIAS2
PKP4
PRKN
PRR35
PSMB1
PTPN21
RCHY1
REL
RNF216
RNF41
SHC1
SLC25A48
SPRY2
SYK
TCF4
TEPSIN
TNKS
TP53BP2
UBB
UBC
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2H
VPS37B
WASL
217 interacting genes:
ABI2
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P1
BYSL
C1orf109
C2CD6
C8orf33
CABP5
CARD9
CATSPER1
CBX8
CCDC187
CCDC198
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CDKN1A
CEP57L1
CFAP206
CHCHD3
CHIC2
CLIP4
CNNM3
COPB1
CSNK1D
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DUSP4
DYRK2
EHHADH
EIF3D
EIF4E2
EXOSC5
FAM107A
FAM124B
FAM161A
FAM214B
FAM221B
FAM50B
FAM74A4
FAM90A1
FANCL
FEM1C
FGF12
FKBP6
FNDC11
FRG1
FRMD6
GADD45GIP1
GATA1
GCC1
GEM
GFI1B
GIPC2
GLIDR
GLYCTK
GMCL2
GNL3L
GPANK1
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HOXB9
HSPD1
IGFN1
INO80B
IQCE
IQCN
KAT5
KAZN
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
LMO3
MAB21L3
MAGEB4
MAPK1
MEMO1
MID2
MORF4L1
MORF4L2
MORN3
MOS
MTA1
MYOZ1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
NTAQ1
OTUB2
PAK5
PATZ1
PHF1
PHF19
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R16A
PPP1R18
PQBP1
PRKAA2
PRKAB2
PRPF18
PRPF31
PRR35
PSMA1
QARS1
RAC1
RAD51D
RAMAC
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3KBP1
SH3RF2
SHFL
SLC15A3
SLC25A6
SLC39A14
SLU7
SMARCB1
SMARCD1
SMIM3
SNHG11
SNW1
SNX31
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
SYT17
TBC1D7
TCEA2
TEAD4
THAP10
THAP7
TLE5
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TSSK2
TSSK3
TTC23
TTLL10
TXNL4A
UBASH3A
UBASH3B
USF2
USP2
UTP14C
VEZF1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZC2HC1C
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF124
ZNF20
ZNF250
ZNF408
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
ZNF648
Entrez ID
84959
84445
HPRD ID
16463
14341
Ensembl ID
ENSG00000154127
ENSG00000107816
Uniprot IDs
Q8TF42
B4DP66
Q9BRK4
PDB IDs
2CPW
2E5K
5VR6
5W5G
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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