ARHGEF39 and TIFA

		ARHGEF39	TIFA
Description		Rho guanine nucleotide exchange factor 39	TRAF interacting protein with forkhead associated domain
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Cell Migration Regulation Of Catalytic Activity	Cytoplasmic Pattern Recognition Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Protein Homooligomerization
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	Alpha-protein kinase 1 signaling pathway
Drugs
Diseases
GWAS			Body mass index ( 26426971) Rheumatoid arthritis ( 30891314)
Interacting Genes		4 interacting genes: CALCOCO2 DVL2 RBPMS TIFA	23 interacting genes: AP1M1 ARHGEF39 DVL2 GSDME IRAK1 KANK2 LNX1 LNX2 NIF3L1 NTAQ1 NUDT18 NXF1 PRKAA2 RIPPLY3 RPL9 SDCBP SDCBP2 TIFAB TNFAIP8 TRAF1 TRAF2 TRAF6 TXN2
Entrez ID		84904	92610
HPRD ID		12929	09835
Ensembl ID		ENSG00000137135	ENSG00000145365
Uniprot IDs		Q8N4T4	Q96CG3
PDB IDs			4YM4 4ZGI 5ZUJ 6A33
Enriched GO Terms of Interacting Partners?
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