PTPN5 and ZBTB5

Data Source:
BioGRID (two hybrid)

		PTPN5	ZBTB5
Description		protein tyrosine phosphatase non-receptor type 5	zinc finger and BTB domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane	Chromatin Nucleus
	Molecular Function	Phosphotyrosine Residue Binding Protein Tyrosine Phosphatase Activity Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Interleukin-37 signaling
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Myopia ( 27182965) Refractive error ( 32231278)	Bipolar disorder ( 31043756)
Interacting Genes		19 interacting genes: CCNQ CLEC4G CUL5 CXCL9 CYB561D2 ENTPD3 FYN MAPK1 MAPK3 MARCHF5 MOB1A PRKN SLC35B1 SNX4 TERF1 TMEM201 TMEM51 VTI1B ZBTB5	10 interacting genes: BAG4 CCDC85B DCX JADE2 METTL5 PPARG PTPN5 ST3GAL3 SWAP70 ZBTB7B
Entrez ID		84867	9925
HPRD ID		01472	08829
Ensembl ID		ENSG00000110786	ENSG00000168795
Uniprot IDs		B7Z2F8 P54829 Q86TL3	O15062 Q5T942
PDB IDs		2BIJ 2BV5 2CJZ 5OVR 5OVX 5OW1 6H8R
Enriched GO Terms of Interacting Partners?
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