PTPN5 and ENTPD3

Data Source:
BioGRID (two hybrid)

		PTPN5	ENTPD3
Description		protein tyrosine phosphatase non-receptor type 5	ectonucleoside triphosphate diphosphohydrolase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Phosphotyrosine Residue Binding Protein Tyrosine Phosphatase Activity Protein Binding	Guanosine-diphosphatase Activity Protein Binding ATP Binding Nucleoside-diphosphatase Activity Nucleoside-triphosphatase Activity Uridine-diphosphatase Activity DATP Phosphohydrolase Activity DCTP Phosphohydrolase Activity DUTP Phosphohydrolase Activity DTTP Phosphohydrolase Activity GTP Phosphohydrolase Activity 8-oxo-dGTP Phosphohydrolase Activity DGTP Phosphohydrolase Activity
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus	Nucleoside Diphosphate Catabolic Process Nucleoside Triphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process
Pathways		Interleukin-37 signaling	Phosphate bond hydrolysis by NTPDase proteins
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Myopia ( 27182965) Refractive error ( 32231278)	Eosinophil percentage of white cells ( 32888494) Neuroticism ( 29255261)
Interacting Genes		19 interacting genes: CCNQ CLEC4G CUL5 CXCL9 CYB561D2 ENTPD3 FYN MAPK1 MAPK3 MARCHF5 MOB1A PRKN SLC35B1 SNX4 TERF1 TMEM201 TMEM51 VTI1B ZBTB5	16 interacting genes: ARL13B CREB3L1 ERGIC3 FAM209A FNDC9 GGT6 GPA33 IFNGR2 LEUTX LHFPL5 LMNA MUC1 PTPN5 STX2 SYNE4 TMEM106A
Entrez ID		84867	956
HPRD ID		01472	16014
Ensembl ID		ENSG00000110786	ENSG00000168032
Uniprot IDs		B7Z2F8 P54829 Q86TL3	O75355
PDB IDs		2BIJ 2BV5 2CJZ 5OVR 5OVX 5OW1 6H8R
Enriched GO Terms of Interacting Partners?
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