RTN4IP1 and RTN4R

Data Source:
HPRD (in vitro)

		RTN4IP1	RTN4R
Description		reticulon 4 interacting protein 1	reticulon 4 receptor
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Anchored Component Of External Side Of Plasma Membrane Neuron Projection Neuronal Cell Body Dendritic Shaft Perikaryon Axonal Growth Cone Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Oxidoreductase Activity	Protein Binding Heparin Binding Chondroitin Sulfate Binding Signaling Receptor Activity Neuregulin Receptor Activity Ganglioside GM1 Binding Ganglioside GT1b Binding
	Biological Process	Nervous System Development Regulation Of Dendrite Development	Cell Surface Receptor Signaling Pathway Negative Regulation Of Neuron Projection Development Corpus Callosum Development Neuronal Signal Transduction Negative Regulation Of Axon Extension Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Negative Regulation Of Axon Regeneration Negative Regulation Of Axonogenesis
Pathways			Axonal growth inhibition (RHOA activation)
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483)	Blood protein levels ( 30072576 29875488) Obesity-related traits ( 23251661)
Interacting Genes		23 interacting genes: ARFGAP3 CALCOCO2 CBFA2T3 CENPK CTAG1A CTAG1B ERMN EXOC7 GGA2 HDX MARCHF5 PPP1R8 PYM1 RELA RTN4 RTN4R RUNX1T1 SCAF1 SMURF2 SORBS1 WBP11 WWTR1 ZYX	9 interacting genes: HOXA1 LINGO1 MAG MGAT5B NGFR OMG OTX1 RTN4 RTN4IP1
Entrez ID		84816	65078
HPRD ID		18008	16123
Ensembl ID		ENSG00000130347	ENSG00000040608
Uniprot IDs		Q8WWV3	Q9BZR6
PDB IDs		2VN8	1OZN 1P8T
Enriched GO Terms of Interacting Partners?
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