OFD1 and LUC7L2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OFD1	LUC7L2
Description		OFD1 centriole and centriolar satellite protein	LUC7 like 2, pre-mRNA splicing factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body	U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding	RNA Binding MRNA Binding Protein Binding Enzyme Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking	MRNA Splice Site Selection
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Oral-facial-digital syndrome 1 Joubert syndrome
GWAS			Diisocyanate-induced asthma ( 25918132)
Interacting Genes		8 interacting genes: CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6	55 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 DZIP1 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B MEOX2 NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRRM4 SRSF6 SRSF7 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10 ZRSR2
Entrez ID		8481	51631
HPRD ID		02162	17456
Ensembl ID		ENSG00000046651	ENSG00000146963
Uniprot IDs		A6NF31 E9KL37 O75665	Q9Y383
PDB IDs
Enriched GO Terms of Interacting Partners?
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