IRS4 and MAGEL2

		IRS4	MAGEL2
Description		insulin receptor substrate 4	MAGE family member L2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleus Endosome Early Endosome Cytosol Retromer Complex
	Molecular Function	Insulin Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Signal Transduction Insulin Receptor Signaling Pathway	Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Positive Regulation Of Actin Nucleation Protein K63-linked Ubiquitination
Pathways		IRS-related events triggered by IGF1R
Drugs
Diseases
GWAS			Menarche (age at onset) ( 25231870) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		22 interacting genes: CRK CRKL CSNK1G2 EGFR ERBB2 GRB2 IGF1R MAGEL2 MTNR1A MTNR1B NDN NISCH PIK3CA PIK3R1 PRKCZ PTEN PTPN11 PTPN6 RNF41 SOCS6 SOCS7 YWHAG	6 interacting genes: FHL2 IRS4 PCGF6 RNF41 SUFU VPS52
Entrez ID		8471	54551
HPRD ID		04620	12008
Ensembl ID		ENSG00000133124	ENSG00000254585
Uniprot IDs		O14654	Q9UJ55
PDB IDs
Enriched GO Terms of Interacting Partners?
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