MAGEL2 and IRS4

		MAGEL2	IRS4
Description		MAGE family member L2	insulin receptor substrate 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endosome Early Endosome Cytosol Retromer Complex	Cytosol Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	Insulin Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding
	Biological Process	Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Positive Regulation Of Actin Nucleation Protein K63-linked Ubiquitination	Signal Transduction Insulin Receptor Signaling Pathway
Pathways			IRS-related events triggered by IGF1R
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		6 interacting genes: FHL2 IRS4 PCGF6 RNF41 SUFU VPS52	22 interacting genes: CRK CRKL CSNK1G2 EGFR ERBB2 GRB2 IGF1R MAGEL2 MTNR1A MTNR1B NDN NISCH PIK3CA PIK3R1 PRKCZ PTEN PTPN11 PTPN6 RNF41 SOCS6 SOCS7 YWHAG
Entrez ID		54551	8471
HPRD ID		12008	04620
Ensembl ID		ENSG00000254585	ENSG00000133124
Uniprot IDs		Q9UJ55	O14654
PDB IDs
Enriched GO Terms of Interacting Partners?
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