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LNX1 and ADAMTSL4
Data Source:
BioGRID
(two hybrid)
LNX1
ADAMTSL4
Description
ligand of numb-protein X 1
ADAMTS like 4
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Interstitial Matrix
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
PDZ Domain Binding
Identical Protein Binding
Metal Ion Binding
Protease Binding
Metalloendopeptidase Activity
Protein Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Epithelial Cell Development
Proteolysis
Apoptotic Process
Extracellular Matrix Organization
Positive Regulation Of Apoptotic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
Ectopia lentis
GWAS
Beard thickness (
26926045
)
Cervical artery dissection (
25420145
)
DNA methylation (variation) (
23725790
)
Heel bone mineral density (
30598549
)
Height (
28552196
)
Peginterferon alfa-2a treatment response in chronic hepatitis B infection (
30972912
)
Uterine fibroids (
30194396
31649266
)
Asthma (
32296059
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Coronary artery disease (
29212778
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (min-P) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Migraine (
27322543
)
Refractive error (
32231278
)
Rhegmatogenous retinal detachment (
23585552
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
474 interacting genes:
ABCA1
ABCB1
ABI2
ABR
ACAT2
ACTN1
ACTN3
ACTN4
ACY3
ADAMTSL4
ADRA1D
AGTRAP
AIDA
AIMP2
AKIRIN2
ALDOC
ALKBH3
AMMECR1L
ANKS1A
AP1M1
APIP
APOL4
APP
ARF3
ARFIP2
ARHGAP6
ARHGEF16
ARVCF
ATPAF2
ATRIP
AURKB
AURKC
AXIN2
BCR
BEND7
BICD2
BIRC2
BLVRA
BLZF1
BORCS6
BPIFA1
BTBD1
C10orf88
C1QTNF1
CA8
CABP5
CADPS
CALCOCO2
CAMK2N2
CARD9
CASP6
CATSPERD
CBX1
CBY1
CBY2
CCBE1
CCDC102B
CCDC33
CCDC85B
CCDC88B
CCDC91
CCNDBP1
CDA
CDC42EP4
CDIPT
CDKN2D
CEP70
CEP72
CEP76
CEP85
CGN
CIB3
CIRBP
CITED1
CLDN1
CLDN17
CLDN2
CLK1
CLK2
CLK3
CMTM5
COIL
CPNE2
CPSF7
CRACR2B
CRX
CTBP1
CTNND2
CTSO
CUTC
CXADR
CYSLTR2
CYSRT1
DAB1
DAPK1
DCTD
DCTPP1
DCUN1D5
DDIT3
DDX17
DENND1B
DEPTOR
DERL1
DEUP1
DHPS
DMC1
DNPEP
DOCK9
DPF2
DRAP1
DRG1
DTX2
DUSP29
DVL3
DYDC1
DYNLT1
EBF4
EDC3
EEF2KMT
EFEMP2
EFHC2
EGLN3
EHMT2
EIF1AD
EIF4A3
EIF4H
ENOX1
ENOX2
EPHB3
EPM2AIP1
EVI5L
EXOC8
EXOSC1
EXOSC4
EXOSC8
FAM118A
FAM124A
FAM90A1
FAM9B
FASN
FBP1
FBXL12
FHL3
FOXP2
FSD2
FXR1
GAS2L2
GDI1
GIPR
GJD2
GJD4
GLRX3
GMCL1
GMNN
GOLPH3L
GPKOW
GPR142
GRAP2
GRB2
GRIN1
GRIPAP1
GUCD1
HDX
HEXIM2
HIP1
HMBOX1
HMG20A
HNRNPF
HNRNPH1
HOMER3
HOMEZ
HOOK2
HOXA1
HSBP1
HSF2BP
HTR2B
HUNK
IGSF5
IHO1
IKZF3
IL16
IL3RA
ILF3
INKA2
INO80E
INSC
IP6K3
ISCU
JAK3
JOSD1
KALRN
KATNAL2
KCNA4
KCTD1
KCTD13
KCTD17
KCTD6
KCTD7
KCTD9
KHDRBS2
KHDRBS3
KIAA1328
KIF24
KIFC3
KLHL12
KPRP
KRT15
KRT16
KRTAP1-1
KRTAP10-8
KRTAP12-3
KRTAP13-3
KRTAP2-3
KRTAP2-4
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
KXD1
LCLAT1
LCP2
LDB2
LDOC1
LEPROTL1
LGALS14
LGR6
LHX2
LNX2
LONRF1
LRRC3B
LRRC73
LSM2
LUZP4
LZTS1
MAD1L1
MAGEA11
MAGEB18
MAPK9
MAPRE2
MEMO1
MEOX2
METTL21A
MID2
MLX
MRFAP1L1
MRPS24
MRPS6
MSANTD4
MSC
MTMR9
MTUS2
MUSTN1
MVB12B
MYEF2
NAB2
NADK
NAGK
NBPF19
NCK2
NDC80
NDOR1
NDUFAB1
NECAB1
NECAB2
NEK6
NKD2
NME1
NME7
NOTCH2NLA
NRCAM
NUDT14
NUMB
NUP37
NUP62
NXT2
ODAD1
ORMDL1
ORMDL3
OSBP2
OSBPL3
OSGIN1
PAFAH1B3
PAICS
PAK5
PBK
PBLD
PCBD1
PDE3B
PDZRN3
PDZRN4
PFDN5
PKDREJ
PKM
PKP4
PLEKHA2
PNMA1
PNMA3
PNMA5
PNMT
POMGNT1
POU6F2
PPIA
PPID
PPIH
PPP1R13B
PQBP1
PRDM14
PRKAR1B
PRKRA
PRMT5
PRPH
PRR13
PRTFDC1
PSMC1
PSME2
PSME3
PSMF1
PTGIR
PTPN11
PTS
PURB
QARS1
RAB33A
RABAC1
RABIF
RAD51D
RAD54B
RALY
RASL11B
RBAK
RBCK1
RBM20
RBMX
RBMY1A1
RBMY1F
RBMY1J
REEP6
RFPL3
RGS20
RIOX2
ROBO3
ROPN1
RPIA
RPS6KA1
RUFY4
RUNDC3A
RUVBL2
S100A3
S100B
SAPCD1
SAT1
SCLT1
SCML1
SCML2
SCNM1
SDK1
SEPTIN1
SGF29
SH2D2A
SHFL
SHTN1
SLC6A15
SLC6A5
SNCB
SNRNP25
SNRPA
SNRPF
SOCS6
SP4
SPG21
SPHKAP
SRSF1
SRSF3
SSNA1
SSTR3
STAC2
STRN
STX5
SUV39H1
SUV39H2
SYCE1L
SYTL2
TACO1
TAX1BP1
TBC1D1
TBCEL
TCF12
TCL1A
TDO2
TEKT4
TGM7
THAP1
THAP7
THG1L
TIFA
TMEM14C
TMEM239
TNFAIP1
TNFAIP3
TNFRSF18
TPM4
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
TRIM10
TRIM14
TRIM21
TRIM23
TRIM27
TRIM3
TRIM39
TRIM42
TRIM50
TRIM54
TRIM60
TRIM68
TRIM8
TRIP13
TRIP6
TRMT12
TSC2
TSC22D4
TSG101
TSN
TSPYL2
TSSK3
TYRO3
UBASH3A
UBE2D2
UBE2D4
UBE2N
UBE2V2
UBP1
ULK2
UPP2
USP54
VASN
VCP
VMAC
VPS37B
VPS52
VRK2
WAC
WDR25
WNT8A
WWP1
YWHAZ
ZADH2
ZBED1
ZBTB2
ZBTB24
ZBTB26
ZBTB43
ZBTB8A
ZCCHC10
ZFP64
ZGPAT
ZNF148
ZNF213
ZNF263
ZNF346
ZNF426
ZNF446
ZNF552
ZNF581
ZNF593
ZNF655
ZRANB1
209 interacting genes:
ADAM12
ADAMTSL5
ALPP
AMMECR1
APOL6
AQP1
ARNT2
ASPSCR1
ATG9A
BAG4
BANF2
BOLA2
BOLA2B
BRME1
CATSPER1
CBX3
CCDC26
CFAP206
CHCHD2
CHERP
CHIC2
CHRD
CHRNG
CLEC18A
COL8A1
CPNE7
CREB5
CST2
CTSB
CXCL16
CYP2S1
CYSRT1
DGCR6
DGCR6L
DIP2A
DLK2
DNPEP
DSCR8
EFEMP2
EIF4E2
EPDR1
ERCC3
EXOSC5
FAH
FAM124B
FARS2
FBLN1
FBXO17
FBXW5
FHL3
FKBP1B
FLNA
FRS3
GATA2
GIP
GLRX3
GLYCTK
GMCL2
GNE
GNG13
GNMT
GOLGA8EP
GSTP1
GUCD1
HEXIM2
HGF
HNRNPLL
HOXA1
HOXC8
HSD3B7
INS
IP6K1
ITGB2
ITGB4
JOSD1
KCTD7
KCTD9
KIF1A
KLHL38
KRTAP1-1
KRTAP1-5
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP19-2
KRTAP21-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
LCE1A
LCE1B
LCE1C
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LGALS14
LHX4
LINC00671
LMO1
LMO2
LMO4
LNX1
LONRF1
LRFN4
LRRC29
MAGOHB
MAPKBP1
MGAT5B
MID2
MKRN3
MORN3
MVP
MYLIP
MYO15B
NATD1
NBPF19
NEK8
NFKBID
NMUR2
NOTCH2NLA
NR4A3
NTAQ1
NTF4
NTN4
NUFIP2
OLFM3
OTX1
PCSK5
PID1
PIN1
PKN1
PLSCR1
PLSCR4
POLD1
POLR1C
POU4F2
PRKAB2
PRR19
PTGER3
PTPMT1
QPRT
R3HDM2
RAB2B
RCHY1
RGL2
RHOJ
RPS19BP1
RUNX1T1
SALL2
SCNM1
SHFL
SLC13A5
SLC23A1
SLC6A20
SLIT1
SMARCC1
SORBS3
SPATA8
SPINK2
SPRY1
SPRY2
STK16
SUSD6
TAPBPL
TCEA2
TFAP2D
TGFB1
THAP6
TMEM150A
TMSB4XP6
TOP3B
TRIM42
TRIM55
TRIM63
TRIP6
TSSK3
TUBGCP4
USP21
VASN
VENTX
VWC2
ZFHX2
ZNF330
ZNF414
ZNF417
ZNF587
Entrez ID
84708
54507
HPRD ID
17287
18237
Ensembl ID
ENSG00000072201
ENSG00000143382
Uniprot IDs
Q8TBB1
A0A669KBE7
B7ZMJ3
Q6UY14
Q9UFG7
PDB IDs
3B76
5H7R
5H7S
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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