FKBP6 and CRACR2A

Data Source:
BioGRID (two hybrid)

		FKBP6	CRACR2A
Description		FKBP prolyl isomerase family member 6 (inactive)	calcium release activated channel regulator 2A
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GO Annotations	Cellular Component	Synaptonemal Complex Cytoplasm Cytosol	Extracellular Region Cytoplasm Membrane Specific Granule Lumen
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding Spermatogenesis Cell Differentiation Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle	Store-operated Calcium Entry Adaptive Immune Response Activation Of Store-operated Calcium Channel Activity Neutrophil Degranulation Positive Regulation Of Calcium Ion Transport
Pathways		Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis	Neutrophil degranulation
Drugs
Diseases
GWAS		Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		37 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 PPP1R32 RAB11FIP2 RNF4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655	35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655
Entrez ID		8468	84766
HPRD ID		05326	10079
Ensembl ID		ENSG00000077800	ENSG00000130038
Uniprot IDs		A0A3B3IST2 O75344	Q9BSW2
PDB IDs		3B7X	6PSD
Enriched GO Terms of Interacting Partners?
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