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FKBP6 and ACD
Data Source:
BioGRID
(two hybrid)
FKBP6
ACD
Description
FKBP prolyl isomerase family member 6 (inactive)
ACD shelterin complex subunit and telomerase recruitment factor
Image
GO Annotations
Cellular Component
Synaptonemal Complex
Cytoplasm
Cytosol
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleoplasm
Telomerase Holoenzyme Complex
Nuclear Body
Shelterin Complex
Molecular Function
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
FK506 Binding
Identical Protein Binding
Hsp90 Protein Binding
Protein Binding
Telomeric DNA Binding
Protein-containing Complex Binding
DNA Polymerase Binding
Biological Process
Protein Peptidyl-prolyl Isomerization
Protein Folding
Spermatogenesis
Cell Differentiation
Gene Silencing By RNA
PiRNA Metabolic Process
DNA Methylation Involved In Gamete Generation
Positive Regulation Of Viral Genome Replication
Meiotic Cell Cycle
Telomere Maintenance
Intracellular Protein Transport
Telomere Maintenance Via Telomerase
Telomere Capping
Protection From Non-homologous End Joining At Telomere
Telomere Assembly
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomerase Activity
Positive Regulation Of Single-stranded Telomeric DNA Binding
Protein Localization To Chromosome, Telomeric Region
Establishment Of Protein Localization To Telomere
Pathways
Meiotic synapsis
PIWI-interacting RNA (piRNA) biogenesis
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Height (
31562340
)
Immune reponse to smallpox (secreted IL-12p40) (
22610502
)
Hemoglobin levels (
32327693
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
37 interacting genes:
ACD
ALDH3A1
CCDC198
CCNK
CDK5RAP3
CFP
CRACR2A
DDIT4L
DLGAP4
ECM1
EEF1D
ENKD1
FAM107A
GAPDH
GSC2
HSP90AA1
IHO1
KANK2
KRT75
LZTS2
MAP3K1
MEI4
MEOX2
NME7
NTAQ1
PIAS2
PICK1
PPP1R32
RAB11FIP2
RNF4
SUMO1P1
TEPSIN
TINF2
TMEM9B
TRIM55
TRIM63
ZNF655
63 interacting genes:
ACTB
ADPRH
AFAP1L2
AIPL1
ANKMY2
ANXA8L1
APOBEC3F
BAG3
CKB
CTTN
DBN1
DBNL
DCX
DPYSL3
EIF3G
EIF4B
ENO2
ENSA
FAM131B
FKBP6
GAPDH
HSP90AB1
IPO5
IVL
LASP1
LDHA
LGALSL
LLGL1
LRRC25
NCDN
NTAQ1
NUDC
NUDCD2
PAGE2
PDLIM2
PEX5
PFKP
PGM2
POT1
RBKS
RECQL4
RGS3
RPSA
SBDS
STIP1
STUB1
SULT1C2
TAGLN
TBC1D10A
TBCD
TINF2
TOMM34
TRIM15
TRIM16
TRIM55
TRIM63
TUBB2A
TUBB4B
USP7
XRCC6
YWHAE
ZFP36L1
ZNF790
Entrez ID
8468
65057
HPRD ID
05326
12417
Ensembl ID
ENSG00000077800
ENSG00000102977
Uniprot IDs
A0A3B3IST2
O75344
A0A590TQL1
Q96AP0
PDB IDs
3B7X
2I46
5H65
5I2X
5I2Y
5UN7
5XYF
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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