CRACR2A and ASB3

Data Source:
BioGRID (two hybrid)

		CRACR2A	ASB3
Description		calcium release activated channel regulator 2A	ankyrin repeat and SOCS box containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Membrane Specific Granule Lumen	Cytosol T-tubule
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process	Store-operated Calcium Entry Adaptive Immune Response Activation Of Store-operated Calcium Channel Activity Neutrophil Degranulation Positive Regulation Of Calcium Ion Transport	Protein Ubiquitination Intracellular Signal Transduction Protein Localization To T-tubule Post-translational Protein Modification Regulation Of Cardiac Muscle Contraction
Pathways		Neutrophil degranulation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Anorexia nervosa ( 31308545) Bronchodilator response in asthma ( 25562107) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Excessive daytime sleepiness ( 27992416) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Interleukin-1-receptor antagonist levels ( 22205395) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Red cell distribution width ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemising ( 31508503) Type 2 diabetes ( 26818947)
Interacting Genes		35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655	9 interacting genes: CRACR2A ENKD1 KDM1A PRMT6 RIN3 TEPSIN TLE5 TNS2 ZAP70
Entrez ID		84766	51130
HPRD ID		10079	05769
Ensembl ID		ENSG00000130038	ENSG00000115239
Uniprot IDs		Q9BSW2	Q9Y575
PDB IDs		6PSD
Enriched GO Terms of Interacting Partners?
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