LMO2 and CORO1C

Data Source:
BioGRID (two hybrid)

		LMO2	CORO1C
Description		LIM domain only 2	coronin 1C
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex	Focal Adhesion Cell Cortex Endosome Membrane Actin Cytoskeleton Lateral Plasma Membrane Flotillin Complex Sarcomere Lamellipodium Vesicle Ruffle Membrane Sarcolemma Synapse
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Transcription Coregulator Binding Transcription Coactivator Activity Protein Binding BHLH Transcription Factor Binding Metal Ion Binding	Protein Binding Small GTPase Binding Actin Filament Binding
	Biological Process	Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus Regulation Of Hematopoietic Stem Cell Differentiation	Neural Crest Cell Migration Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Phagocytosis Actin Filament Organization Signal Transduction Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial Cell Migration Regulation Of Fibroblast Migration Endosomal Transport Cell Migration Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Establishment Of Protein Localization Regulation Of Focal Adhesion Assembly Negative Regulation Of Focal Adhesion Assembly Membrane Fission Activation Of GTPase Activity Endosome Membrane Tubulation Endosome Fission Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Ruffle Assembly Positive Regulation Of Lamellipodium Morphogenesis
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Cognitive performance ( 19734545) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252)	Acne (severe) ( 24927181) Brain morphology (MOSTest) ( 32665545) Coronary artery disease and LDL cholesterol levels (multivariate analysis) ( 30525989) Hemoglobin ( 32888494) Immature fraction of reticulocytes ( 32888494) Low high density lipoprotein cholesterol levels ( 26879886) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		188 interacting genes: ABI2 ADAMTSL4 AFDN AGTRAP AIMP2 ALDH6A1 ARHGEF5 ARID5A ARNT2 AXIN1 BANP BCAS2 BEX2 BLZF1 BYSL C1orf109 C1orf94 CALCOCO2 CBY2 CCDC33 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DMRT3 DRAP1 DYDC1 EFHC1 EFHC2 EHMT2 EIF3B EIF4EBP1 ELF2 ENKD1 ERBIN FAAP20 FAM214B FAM228A FAM90A1 FHL3 FHL5 GAS8 GATA1 GATA2 GATA3 GFAP GMEB2 GOLGA2 GRB2 HDAC5 HNRNPC HNRNPM HOOK1 ICA1L IFT43 IHO1 IKZF1 IKZF3 INCA1 ISL1 ISY1 KANK2 KAZN KDM5A KIF2A KIF3B KPRP KRT15 KRT34 KRT40 KRT75 KRT80 KRTAP10-7 LDB1 LDB2 LDOC1 LMO4 LMOD3 LYL1 LZTS1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MISP MRFAP1L1 MSN MTUS2 MYOZ3 N4BP2L2 NCAPH2 NDOR1 NDUFAB1 NDUFB7 NFKBID NHLH1 NIF3L1 NOTCH2NLA NOXA1 NSMF NTAQ1 NUP62 NUTM1 PATZ1 PAX9 PBX4 PDE9A PHC2 POLR2G PPP1R32 PRDM6 PRKG1 PSMA1 RBBP8 RCN1 REL RELA RINT1 RLIM ROCK1 RTL8C RUSC1 SAXO1 SGTB SKP1 SMAD2 SMUG1 SNAPC5 SOX5 SP1 SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TBX2 TCP10L TEKT3 TFIP11 TFPT THAP6 TLE5 TLX3 TRIB3 TRIM23 TRIM54 TRIM55 TRIM63 TRIP6 TSC1 TSC22D4 TSEN15 TSEN54 TSGA10IP TSPYL2 TSSK3 TUFT1 UBA6 UBASH3B UBE2I USH1G VBP1 VEZF1 VMAC WASF1 WASHC1 YOD1 YPEL3 ZFP64 ZMYND12 ZNF185 ZNF19 ZNF24 ZNF250 ZNF34 ZNF410 ZNF641 ZNF655 ZNF688	3 interacting genes: ERCC6 LMO2 RAC1
Entrez ID		4005	23603
HPRD ID		01586	09244
Ensembl ID		ENSG00000135363	ENSG00000110880
Uniprot IDs		P25791	A0A024RBI5 Q9ULV4
PDB IDs		2XJY 2XJZ 2YPA 4KFZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?