GLYR1 and NSD3

Data Source:
BioGRID (two hybrid)

		GLYR1	NSD3
Description		glyoxylate reductase 1 homolog	nuclear receptor binding SET domain protein 3
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GO Annotations	Cellular Component	Nucleosome Nucleoplasm Cytosol	Chromatin Nucleus Nucleoplasm
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Nucleosome Binding Methylated Histone Binding Histone Binding NADP Binding NAD Binding	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity
	Biological Process	Positive Regulation Of Histone Acetylation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Cancer ( 29299148) Night sleep phenotypes ( 27126917)
Interacting Genes		13 interacting genes: ARL16 CCNC CDKN2D CFAP206 CLIC3 EIF1AD FHL2 GEMIN4 H3-4 H3C1 KDM1A NSD3 NTMT1	42 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557
Entrez ID		84656	54904
HPRD ID		17625	06155
Ensembl ID		ENSG00000140632	ENSG00000147548
Uniprot IDs		D3DUE6 Q49A26 Q9NZ78	Q9BZ95
PDB IDs		2UYY 4GUR 4GUS 4GUT 4GUU 4HSU 6R1U 6R25	2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR
Enriched GO Terms of Interacting Partners?
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