NSD3 and MNDA

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		NSD3	MNDA
Description		nuclear receptor binding SET domain protein 3	myeloid cell nuclear differentiation antigen
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Extracellular Region Nucleoplasm Nucleolus Cytosol Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity	Double-stranded DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation	Activation Of Innate Immune Response Cellular Defense Response Cellular Response To DNA Damage Stimulus Negative Regulation Of B Cell Proliferation Positive Regulation Of Interleukin-1 Beta Production Cellular Response To Interferon-beta Positive Regulation Of Apoptotic Process Neutrophil Degranulation B Cell Receptor Signaling Pathway
Pathways		PKMTs methylate histone lysines	Neutrophil degranulation
Drugs
Diseases
GWAS			Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Perceived intensity of aspartame ( 31005972)
Interacting Genes		42 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557	13 interacting genes: CDK1 CDK2 CRK FBXO7 HOXB2 MAPK8IP2 NSD3 PRMT6 PRMT7 RB1 RBL2 STAT3 TP53
Entrez ID		54904	4332
HPRD ID		06155	15932
Ensembl ID		ENSG00000147548	ENSG00000163563
Uniprot IDs		Q9BZ95	P41218 Q5VUU6
PDB IDs		2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR	2DBG 5H7Q 5WPZ
Enriched GO Terms of Interacting Partners?
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