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CUL2 and KHNYN
Data Source:
BioGRID
(pull down)
CUL2
KHNYN
Description
cullin 2
KH and NYN domain containing
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytosol
SCF Ubiquitin Ligase Complex
VCB Complex
Cullin-RING Ubiquitin Ligase Complex
Cul2-RING Ubiquitin Ligase Complex
Cellular_component
Nucleus
Cytoplasmic Ribonucleoprotein Granule
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Protein-containing Complex Binding
Molecular_function
MRNA Binding
Endoribonuclease Activity
Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Viral Process
Protein Ubiquitination
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Post-translational Protein Modification
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Intrinsic Apoptotic Signaling Pathway
Biological_process
RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Neddylation
Regulation of expression of SLITs and ROBOs
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Interacting Genes
25 interacting genes:
ARID1B
CAND1
CDC34
COMMD1
COPS5
DCUN1D2
DCUN1D3
DCUN1D4
DCUN1D5
E2F1
ELOC
GPS1
KAT2A
KHNYN
MKNK2
NEDD8
RBX1
RNF7
SAP130
SENP8
UBC
UBE2D1
VHL
ZER1
ZYG11B
4 interacting genes:
CUL1
CUL2
PLOD3
TEPSIN
Entrez ID
8453
23351
HPRD ID
06786
11076
Ensembl ID
ENSG00000108094
ENSG00000100441
Uniprot IDs
A0A0A0MTN0
A0A140VKB1
B7Z1Y1
Q13617
A8K6L5
O15037
PDB IDs
4WQO
5N4W
6R6H
6R7F
6R7H
6R7I
6R7N
2N5M
2N7K
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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