KHNYN and PLOD3

Data Source:
BioGRID (two hybrid)

		KHNYN	PLOD3
Description		KH and NYN domain containing	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
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GO Annotations	Cellular Component	Cellular_component Nucleus Cytoplasmic Ribonucleoprotein Granule	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Molecular_function MRNA Binding Endoribonuclease Activity Protein Binding	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity
	Biological Process	Biological_process RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Protein Phosphopantetheinylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Lung Morphogenesis Basement Membrane Assembly
Pathways			Collagen biosynthesis and modifying enzymes
Drugs			Ascorbic acid
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		4 interacting genes: CUL1 CUL2 PLOD3 TEPSIN	20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620
Entrez ID		23351	8985
HPRD ID		11076	04347
Ensembl ID		ENSG00000100441	ENSG00000106397
Uniprot IDs		A8K6L5 O15037	O60568 Q9UG85
PDB IDs		2N5M 2N7K	6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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