CHAC1 and RHOXF2

Data Source:
HPRD (two hybrid)

		CHAC1	RHOXF2
Description		ChaC glutathione specific gamma-glutamylcyclotransferase 1	Rhox homeobox family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Trans-Golgi Network Cytosol	Chromatin Nucleus
	Molecular Function	Gamma-glutamylcyclotransferase Activity Notch Binding Protein Binding Glutathione Specific Gamma-glutamylcyclotransferase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Glutathione Biosynthetic Process Glutathione Catabolic Process Response To Unfolded Protein Notch Signaling Pathway Negative Regulation Of Protein Processing Neurogenesis Negative Regulation Of Notch Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression
Pathways		Glutathione synthesis and recycling Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS		FEV1 ( 30804560) Lung function (FVC) ( 30804560) Malaria ( 31844061) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		1 interacting genes: RHOXF2	101 interacting genes: ARID5A ARMCX2 ARSA ATN1 ATXN1 BATF3 BOLL C1orf94 CAMK2A CCDC33 CCNK CEACAM6 CERCAM CHAC1 CLASRP CLDN7 CREM CRX CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FAM166A FAM168A FAM168B FBF1 HNRNPLL HOXC13 HYPK KHDC4 KLHDC7B KRTAP12-2 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP7-1 LASP1 LENG8 LSM4 LZTS2 MAGED1 MDFI MED7 MGAT5B MSX2 MVP NANOG NEU4 NKX1-2 NKX3-1 PITX1 PLAC8 PLOD3 POLR3D POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS RBPMS2 RNF4 SERF2 SNAPC1 SUMO1 TENT5A TENT5B TENT5C TENT5D TEP1 TLE5 TMCC2 TOLLIP TRIP13 UBAP2 UBE2I UPF1 UTP6 VAC14 VENTX VPS25 ZBTB32 ZNF683
Entrez ID		79094	84528
HPRD ID		14634	02345
Ensembl ID		ENSG00000128965	ENSG00000131721
Uniprot IDs		Q9BUX1	Q9BQY4
PDB IDs
Enriched GO Terms of Interacting Partners?
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