NIFK and MKI67

		NIFK	MKI67
Description		nucleolar protein interacting with the FHA domain of MKI67	marker of proliferation Ki-67
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GO Annotations	Cellular Component	Condensed Nuclear Chromosome Nucleoplasm Chromosome Nucleolus Cytoplasm	Condensed Chromosome Nucleus Nucleoplasm Chromosome Nucleolus Membrane Nuclear Body
	Molecular Function	RNA Binding Protein Binding	DNA Binding RNA Binding Protein Binding ATP Binding Protein C-terminus Binding
	Biological Process	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Transcription RRNA Metabolic Process Protein-containing Complex Assembly	Cell Cycle Regulation Of Mitotic Nuclear Division Cell Population Proliferation Regulation Of Chromosome Segregation Regulation Of Chromatin Organization
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease in APOE e4- carriers ( 25778476) Drug experimentation measurement ( 30718321) Lead levels ( 26025379) Select biomarker traits ( 17903293) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		3 interacting genes: MKI67 TNIP1 ZDHHC17	14 interacting genes: CBX3 CBX5 CDK1 ECPAS HINFP KIF15 NIFK PRKCB PTEN SMN1 SUMO2 TK1 TRIM55 TRIM63
Entrez ID		84365	4288
HPRD ID		17576	08902
Ensembl ID		ENSG00000155438	ENSG00000148773
Uniprot IDs		Q9BYG3	P46013
PDB IDs		2AFF	1R21 2AFF 5J28
Enriched GO Terms of Interacting Partners?
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