MKI67 and KIF15

Data Source:
HPRD (in vivo, two hybrid)

		MKI67	KIF15
Description		marker of proliferation Ki-67	kinesin family member 15
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GO Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm Chromosome Nucleolus Membrane Nuclear Body	Centrosome Spindle Cytosol Kinesin Complex Plus-end Kinesin Complex Microtubule Membrane
	Molecular Function	DNA Binding RNA Binding Protein Binding ATP Binding Protein C-terminus Binding	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Cell Cycle Regulation Of Mitotic Nuclear Division Cell Population Proliferation Regulation Of Chromosome Segregation Regulation Of Chromatin Organization	Mitotic Cell Cycle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways			MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Drug experimentation measurement ( 30718321) Lead levels ( 26025379) Select biomarker traits ( 17903293) Triglyceride levels x loop diuretics use interaction ( 31806883)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Bone mineral density (hip) ( 30172743) Face memory ( 31596458) Idiopathic pulmonary fibrosis ( 31710517) Pulse pressure ( 30224653 30578418) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		14 interacting genes: CBX3 CBX5 CDK1 ECPAS HINFP KIF15 NIFK PRKCB PTEN SMN1 SUMO2 TK1 TRIM55 TRIM63	5 interacting genes: CEP126 CHD3 MAP1LC3A MKI67 VIM
Entrez ID		4288	56992
HPRD ID		08902	10037
Ensembl ID		ENSG00000148773	ENSG00000163808
Uniprot IDs		P46013	C9JKA9 Q9NS87
PDB IDs		1R21 2AFF 5J28	4BN2
Enriched GO Terms of Interacting Partners?
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