RECK and SSC4D

Data Source:
BioGRID (two hybrid)

		RECK	SSC4D
Description		reversion inducing cysteine rich protein with kazal motifs	scavenger receptor cysteine rich family member with 4 domains
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Anchored Component Of Membrane Wnt Signalosome	Extracellular Region Membrane
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Wnt-protein Binding Coreceptor Activity Involved In Canonical Wnt Signaling Pathway	Scavenger Receptor Activity
	Biological Process	Blood Vessel Maturation Sprouting Angiogenesis Embryo Implantation Extracellular Matrix Organization Negative Regulation Of Cell Migration Embryonic Forelimb Morphogenesis Regulation Of Angiogenesis Canonical Wnt Signaling Pathway Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Metalloendopeptidase Activity	Endocytosis
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172) IgG glycosylation ( 23382691)
Interacting Genes		42 interacting genes: ADAM12 BMF C22orf39 CCN3 CEP44 CFP CTH CTIF CYSRT1 DISC1 EFHC2 GLRX3 INCA1 KEAP1 KLHL20 KRT40 KRTAP10-8 KRTAP13-2 KRTAP26-1 KRTAP3-1 LCN1 MEOX2 MLPH MMP9 MTNR1B NBPF19 NDUFB7 NOTCH2NLA NR4A3 NUDT16L1 OXER1 PRIM2 REL SPSB2 SSC4D TCF4 TEKT4 TRIM39 TRIM69 USHBP1 ZNF438 ZNF704	32 interacting genes: ATXN7L2 CATSPER1 CNNM3 COL8A1 CREB5 CYSRT1 ENKD1 GNE HAPLN2 HOXA1 HSD3B7 KRTAP10-8 KRTAP12-4 KRTAP13-2 KRTAP26-1 KRTAP3-3 MGAT5B NFKBID PCSK5 PLEKHN1 PLSCR4 PRKAB2 PTPMT1 RECK RHOU STK16 TEKT5 TFAP2D TLE5 TRIP13 TROAP VASN
Entrez ID		8434	136853
HPRD ID		05567	06364
Ensembl ID		ENSG00000122707	ENSG00000146700
Uniprot IDs		A8K9D8 O95980 Q6P9E2	Q8WTU2
PDB IDs
Enriched GO Terms of Interacting Partners?
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