EIF1AD and ZNF521

Data Source:
BioGRID (two hybrid)

		EIF1AD	ZNF521
Description		eukaryotic translation initiation factor 1A domain containing	zinc finger protein 521
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton	Nucleus
	Molecular Function	Translation Initiation Factor Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Translational Initiation	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment
Pathways			RUNX2 regulates osteoblast differentiation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Serum uric acid levels ( 32271837)	Adverse response to lamotrigine and phenytoin ( 22379998) Chronotype ( 30696823) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Height ( 31562340) High density lipoprotein cholesterol levels ( 30498476) Mitochondrial DNA levels ( 25240745) Myeloproliferative neoplasms ( 33057200) Nickel levels ( 26025379) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Systemic juvenile idiopathic arthritis ( 27927641) Takayasu arteritis ( 25604533) Toenail selenium levels ( 25343990) Urgency urinary incontinence ( 25524241)
Interacting Genes		34 interacting genes: AP2M1 BEND7 CCDC106 CEP55 CEP76 DPPA2 GAS8 GCSAML GLYR1 GTF2H4 LNX1 MEOX2 MID2 MREG PAX6 PBX4 PICK1 PINX1 RASSF10 RBAK RBM48 SDCBP SDCBP2 STAT1 STX11 TBC1D5 TEPSIN TLE5 TNNI1 ZBTB14 ZBTB8A ZNF280A ZNF521 ZNF558	8 interacting genes: BRAP EBF1 EIF1AD GATA1 LYST RARS1 SMAD1 SMAD4
Entrez ID		84285	25925
HPRD ID		14411	18350
Ensembl ID		ENSG00000175376	ENSG00000198795
Uniprot IDs		A0A024R5B9 Q8N9N8	J3KTI4 Q8IYZ2 Q96K83
PDB IDs		2DGY
Enriched GO Terms of Interacting Partners?
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