ZNF521 and RARS1

Data Source:
BioGRID (two hybrid)

		ZNF521	RARS1
Description		zinc finger protein 521	arginyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Domain Specific Binding Metal Ion Binding	TRNA Binding Arginine-tRNA Ligase Activity Protein Binding ATP Binding Arginine Binding Cadherin Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment	TRNA Aminoacylation For Protein Translation Arginyl-tRNA Aminoacylation
Pathways		RUNX2 regulates osteoblast differentiation	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Chronotype ( 30696823) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Height ( 31562340) High density lipoprotein cholesterol levels ( 30498476) Mitochondrial DNA levels ( 25240745) Myeloproliferative neoplasms ( 33057200) Nickel levels ( 26025379) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Systemic juvenile idiopathic arthritis ( 27927641) Takayasu arteritis ( 25604533) Toenail selenium levels ( 25343990) Urgency urinary incontinence ( 25524241)
Interacting Genes		8 interacting genes: BRAP EBF1 EIF1AD GATA1 LYST RARS1 SMAD1 SMAD4	77 interacting genes: AIMP1 CCDC115 CDC42 EPRS1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I QARS1 SUMO2 ZNF521
Entrez ID		25925	5917
HPRD ID		18350	00142
Ensembl ID		ENSG00000198795	ENSG00000113643
Uniprot IDs		J3KTI4 Q8IYZ2 Q96K83	P54136
PDB IDs			4Q2T 4Q2X 4Q2Y 4R3Z 4ZAJ
Enriched GO Terms of Interacting Partners?
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