EIF1AD and PBX4

Data Source:
BioGRID (two hybrid)

		EIF1AD	PBX4
Description		eukaryotic translation initiation factor 1A domain containing	PBX homeobox 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton	Chromatin XY Body Nucleus
	Molecular Function	Translation Initiation Factor Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding
	Biological Process	Translational Initiation	Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Animal Organ Morphogenesis Positive Regulation Of Transcription, DNA-templated Embryonic Organ Development Neuron Development
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Serum uric acid levels ( 32271837)	Attention deficit hyperactivity disorder symptom score ( 27663945) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Cholesterol, total ( 20686565) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) LDL cholesterol ( 18193044 19060906 20686565) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Obesity-related traits ( 23251661) Perceived unattractiveness to mosquitoes ( 28199695) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Schizophrenia ( 25056061 29483656 23974872) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Total cholesterol levels ( 30275531) Triglyceride levels (parental genotype effect) ( 30255771) Triglyceride levels in response to fenofibrate treatment (parental genotype effect) ( 30255771) Triglycerides ( 18193044 19060906 20686565)
Interacting Genes		34 interacting genes: AP2M1 BEND7 CCDC106 CEP55 CEP76 DPPA2 GAS8 GCSAML GLYR1 GTF2H4 LNX1 MEOX2 MID2 MREG PAX6 PBX4 PICK1 PINX1 RASSF10 RBAK RBM48 SDCBP SDCBP2 STAT1 STX11 TBC1D5 TEPSIN TLE5 TNNI1 ZBTB14 ZBTB8A ZNF280A ZNF521 ZNF558	65 interacting genes: ARHGEF3 BCL6 BFSP2 C14orf119 C1orf109 CCM2L CDKN2C CHCHD2 CLCNKA CPNE7 EIF1AD EIF3B EIF3F EXOC8 GADD45GIP1 GEM GINS4 GPANK1 HOXB2 HOXB5 HOXC5 HOXC8 HOXD4 HSBP1L1 IFT20 IPO13 KDM1A KLHL38 LMO2 MAGOHB MAPK9 MBD3 MEIS2 MIPOL1 NCK2 NEK6 NUTF2 OSTF1 PACSIN2 PICK1 PIH1D2 PIK3R3 PKNOX1 PKNOX2 PPL RANBP3 RBX1 RIPPLY1 RIPPLY2 SCNM1 SERTAD1 SMARCD1 SPANXN2 SPANXN3 SPG21 TFIP11 TRIM41 TSEN15 TSSK3 TXNDC9 UBTFL1 USHBP1 USP20 WWOX ZNF330
Entrez ID		84285	80714
HPRD ID		14411	16287
Ensembl ID		ENSG00000175376	ENSG00000105717
Uniprot IDs		A0A024R5B9 Q8N9N8	Q9BYU1
PDB IDs		2DGY
Enriched GO Terms of Interacting Partners?
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