TMEM79 and CLEC7A

Data Source:
BioGRID (two hybrid)

		TMEM79	CLEC7A
Description		transmembrane protein 79	C-type lectin domain containing 7A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Trans-Golgi Network Membrane	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	(1->3)-beta-D-glucan Binding Protein Binding Carbohydrate Binding Pattern Recognition Receptor Activity MHC Protein Binding Metal Ion Binding
	Biological Process	Epithelial Cell Maturation Hair Follicle Morphogenesis Cuticle Development Regulated Exocytosis Positive Regulation Of Epidermis Development Establishment Of Skin Barrier Cornification	Leukocyte Activation Involved In Immune Response Positive Regulation Of Dendritic Cell Cytokine Production Phagocytosis, Recognition Inflammatory Response Cell Recognition Positive Regulation Of Cell Population Proliferation Carbohydrate Mediated Signaling Positive Regulation Of Gene Expression Detection Of Fungus Positive Regulation Of Cell Migration Positive Regulation Of Protein-containing Complex Assembly Detection Of Molecule Of Fungal Origin Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Superoxide Anion Generation T Cell Activation Defense Response To Protozoan Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Innate Immune Response Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Phagocytosis Positive Regulation Of Lymphocyte Activation Positive Regulation Of Killing Of Cells Of Other Organism Positive Regulation Of Respiratory Burst Cellular Response To Molecule Of Fungal Origin Positive Regulation Of Monocyte Chemotactic Protein-1 Production Positive Regulation Of Wound Healing Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Cell Maturation
Pathways			CLEC7A (Dectin-1) signaling CLEC7A (Dectin-1) signaling
Drugs
Diseases			Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS		Glycated hemoglobin levels ( 24647736 28898252 29170429) Mean corpuscular hemoglobin concentration ( 20139978)
Interacting Genes		36 interacting genes: ABO AMIGO1 ANKRD46 APOD ARL13B BRICD5 CLEC7A COQ9 CPLX4 CYB5R3 FAM209A FNDC9 GIMAP1 GPRC5D LDLRAD1 LPAR3 PELI2 PLN PLP2 PVR RNF8 RPRM SEC22A SERP1 SFTPC SLN TEX264 TMEM100 TMEM14C TMEM254 TMEM97 TMPRSS2 TMPRSS4 TNMD TRAM1L1 ZCCHC12	47 interacting genes: ADAM33 AIP ARL13B ASGR2 BNIP3 BNIP3L C14orf180 CALM3 CD53 CD74 CTXN3 CXCL9 FAM3A FCGR1A FNDC9 GJB1 HSPD1 IFNGR2 IL1RL1 JAGN1 KLRC1 KTN1 MTIF3 NEMP1 NINJ2 NSG2 OCLN OLFM4 OPRM1 PTTG1IP RANBP9 RHOU SAR1A SEC22A SGCB SMIM3 SPINT1 SUSD3 SYNE4 TEX29 TLCD4 TMEM79 TMPRSS2 TMPRSS4 UPK2 VSIR ZFPL1
Entrez ID		84283	64581
HPRD ID		17481	08396
Ensembl ID		ENSG00000163472	ENSG00000172243
Uniprot IDs		Q9BSE2	A0A024RAN9 A0A0S2Z5Q1 Q68D78 Q9BXN2
PDB IDs
Enriched GO Terms of Interacting Partners?
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