POLR1B and ZNF207

Data Source:
BioGRID (two hybrid)

		POLR1B	ZNF207
Description		RNA polymerase I subunit B	zinc finger protein 207
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Cytosol	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Nucleolus Cytoplasm Spindle Microtubule Spindle Matrix
	Molecular Function	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ribonucleoside Binding Metal Ion Binding	DNA Binding RNA Binding Protein Binding Microtubule Binding Metal Ion Binding
	Biological Process	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Embryo Implantation RRNA Transcription Nucleologenesis Positive Regulation Of Gene Expression, Epigenetic	Mitotic Sister Chromatid Segregation Microtubule Bundle Formation Mitotic Spindle Assembly Checkpoint Attachment Of Spindle Microtubules To Kinetochore Microtubule Polymerization Protein Stabilization Cell Division Regulation Of Chromosome Segregation Mitotic Spindle Assembly
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS			Survival in pancreatic cancer ( 28470677)
Interacting Genes		14 interacting genes: AKT2 CCND1 EIF3L ESR1 GIT2 HDAC6 LDB1 LZTR1 MED20 NFKBIB POLR1E RPL37 RRN3 ZNF207	9 interacting genes: ERBB3 HNRNPM HNRNPUL1 MAP2K2 POLR1B TET2 UBR5 WBP4 WDR77
Entrez ID		84172	7756
HPRD ID		06852	04576
Ensembl ID		ENSG00000125630	ENSG00000010244
Uniprot IDs		B7Z1W6 Q9H9Y6	O43670
PDB IDs
Enriched GO Terms of Interacting Partners?
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