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TMEM222 and CLDN5
Data Source:
BioGRID
(two hybrid)
TMEM222
CLDN5
Description
transmembrane protein 222
claudin 5
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Integral Component Of Membrane
Apicolateral Plasma Membrane
Cell Junction
Cortical Actin Cytoskeleton
Tight Junction
Molecular Function
Protein Binding
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Biological Process
Outflow Tract Morphogenesis
Cell-cell Junction Assembly
Cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Learning
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Positive Regulation Of Protein Binding
Maintenance Of Blood-brain Barrier
Negative Regulation Of Vascular Permeability
Roof Of Mouth Development
Face Morphogenesis
Bicellular Tight Junction Assembly
Tight Junction Assembly
Positive Regulation Of Establishment Of Endothelial Barrier
Positive Regulation Of Bicellular Tight Junction Assembly
Establishment Of Blood-retinal Barrier
Regulation Of Bicellular Tight Junction Assembly
Pathways
Tight junction interactions
RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Alanine aminotransferase levels (
31219225
)
Interacting Genes
38 interacting genes:
ABHD16A
AQP6
BIK
BSCL2
CD79A
CLDN5
CLRN1
COMT
CRB3
CREB3
CREB3L1
EBP
ELOVL4
ERG28
ERGIC3
EVI2B
FAM174A
FAM209A
HIBADH
HSD17B13
KIR2DL3
LMNA
LRRC59
NCR3LG1
PEX12
PRSS23
PTGES
RETREG3
RNASEK
SLC10A1
SLC10A2
SSMEM1
STX1A
TMEM14B
TMEM35A
TMPRSS2
TMX2
ZDHHC15
40 interacting genes:
AQP1
BTNL8
CCDC167
CLDN3
CLRN2
CNPY3
CORIN
CTRL
CXCL9
CYB561A3
EFNA5
EHHADH
ERG28
ERMP1
FXYD6-FXYD2
GYPA
LAT
LHFPL5
MIP
MPDZ
PLP2
PLPPR2
PMP22
RPRM
SFTPC
SGCG
SLC35B4
SMIM3
TECR
TF
TJP1
TMEM128
TMEM140
TMEM14C
TMEM182
TMEM190
TMEM222
TSPAN2
VAMP5
YIPF1
Entrez ID
84065
7122
HPRD ID
13167
03654
Ensembl ID
ENSG00000186501
ENSG00000184113
Uniprot IDs
Q9H0R3
D3DX19
O00501
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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