CTTNBP2 and MEI4

Data Source:
BioGRID (two hybrid)

		CTTNBP2	MEI4
Description		cortactin binding protein 2	meiotic double-stranded break formation protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cortex Synaptic Vesicle Dendritic Spine Postsynaptic Actin Cytoskeleton Glutamatergic Synapse	Lateral Element
	Molecular Function	Protein Binding SH3 Domain Binding	Protein Binding
	Biological Process	Brain Development Regulation Of Modification Of Postsynaptic Actin Cytoskeleton	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) General factor of neuroticism ( 30867560) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 29891935) Idiopathic osteonecrosis of the femoral head ( 28000841) Intraocular pressure ( 29617998 29785010 31959993 30054594) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 30108155) Type 2 diabetes ( 30054458 30297969) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Macular thickness ( 30535121)
Interacting Genes		10 interacting genes: APPL1 ARNTL2 CTTN FAM86C1P HSF2BP INCA1 KRT14 MAGEA11 MEI4 PKNOX2	36 interacting genes: AFMID BAG4 C19orf25 C1orf109 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C
Entrez ID		83992	101928601
HPRD ID		09890
Ensembl ID		ENSG00000077063	ENSG00000269964
Uniprot IDs		Q20BG9 Q8WZ74	A8MW99
PDB IDs
Enriched GO Terms of Interacting Partners?
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