MEI4 and OSGIN1

Data Source:
BioGRID (two hybrid)

		MEI4	OSGIN1
Description		meiotic double-stranded break formation protein 4	oxidative stress induced growth inhibitor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lateral Element	Cellular_component
	Molecular Function	Protein Binding	Protein Binding Growth Factor Activity
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis	Signal Transduction Multicellular Organism Development Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Macular thickness ( 30535121)	LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		36 interacting genes: AFMID BAG4 C19orf25 C1orf109 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C	47 interacting genes: AKT1 ARNT2 ATM BCAR3 BEND7 BTBD2 CAPN3 CCDC33 CENPN CRX DECR2 DNAJA3 FGFR4 GCLM HOMEZ IKBKG IKZF3 INCA1 KATNBL1 KRAS KRT75 LNX1 MEI4 MEIS2 MEOX1 MEOX2 MTERF4 PAX5 PDE4A PDE4C PICK1 POLDIP3 POLR2G PPM1D PTEN REL SAXO1 SMARCB1 SORBS3 TCF12 TCF4 TLE5 TRIM54 XRCC3 ZBTB42 ZC2HC1C ZKSCAN4
Entrez ID		101928601	29948
HPRD ID			06412
Ensembl ID		ENSG00000269964	ENSG00000140961
Uniprot IDs		A8MW99	Q9UJX0
PDB IDs
Enriched GO Terms of Interacting Partners?
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