IMMP2L and HNRNPD

Data Source:
BioGRID (two hybrid)

		IMMP2L	HNRNPD
Description		inner mitochondrial membrane peptidase subunit 2	heterogeneous nuclear ribonucleoprotein D
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Mitochondrial Inner Membrane Peptidase Complex	Nucleus Nucleoplasm Cytosol Synapse Ribonucleoprotein Complex
	Molecular Function	Serine-type Endopeptidase Activity Peptidase Activity	Minor Groove Of Adenine-thymine-rich DNA Binding Chromatin Binding RNA Binding Protein Binding Transcription Factor Binding MRNA 3'-UTR AU-rich Region Binding Telomeric DNA Binding Histone Deacetylase Binding
	Biological Process	Ovarian Follicle Development Signal Peptide Processing Protein Processing Involved In Protein Targeting To Mitochondrion Superoxide Metabolic Process Cellular Response To DNA Damage Stimulus Spermatogenesis Brain Development Blood Circulation Respiratory Electron Transport Chain Ovulation Mitochondrial Respiratory Chain Complex Assembly Cerebellum Vasculature Development	MRNA Splicing, Via Spliceosome Liver Development Regulation Of Transcription, DNA-templated RNA Processing RNA Catabolic Process Regulation Of Gene Expression RNA Metabolic Process Cerebellum Development Regulation Of Telomere Maintenance Regulation Of Circadian Rhythm Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Response To Calcium Ion Response To Electrical Stimulus 3'-UTR-mediated MRNA Destabilization Cellular Response To Amino Acid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Nitric Oxide Circadian Regulation Of Translation Response To Rapamycin Positive Regulation Of Telomere Capping Response To Sodium Phosphate Cellular Response To Putrescine Positive Regulation Of Telomerase RNA Reverse Transcriptase Activity Hepatocyte Dedifferentiation
Pathways			mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs			Artenimol
Diseases
GWAS		Alzheimer's disease in APOE e4+ carriers ( 25778476) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body size at age 10 ( 32376654) Cadmium levels ( 26025379) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive performance ( 19734545) Migraine ( 27322543) Night sleep phenotypes ( 27126917) Schizophrenia ( 28991256 25056061 29483656 30285260)	Chronotype ( 30696823) Coronary artery disease ( 32469254 33020668) Morning person ( 30696823) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: HNRNPD	87 interacting genes: ABCC10 ACTB ADGRE5 ARF4 B3GAT3 BCL2 BET1L BRCA1 C1QBP CAPN1 CD81 CINP COG7 COL18A1 CSDE1 CTSB CUTA DGCR2 DHX30 DMAC1 EEF2 ERG ESR1 EXOSC4 FBXL15 FLNA GSK3B GTF3C3 GTSE1 GUK1 HBZ HDAC1 HIRA HMGA1 HNRNPF HNRNPH3 HSPA4 HSPB1 HSPB2 IGF2BP2 IL7R IMMP2L IMMT ING4 LDHA LSM5 MAP2K1 MAPK6 MEOX2 MPP1 MTA2 NTMT1 P4HB PABPC1 PCBP1 PCBP2 PCSK7 PDLIM7 PEX10 PPOX PRDX3 PRKACA PTBP2 PYCR1 RALY RPSA SAFB SDF2 SEPTIN9 SF3B4 SFN SHISA5 SLC27A5 SLC3A2 SNAPC4 SNRPC SREK1 SUMO4 SYNCRIP TNPO1 TRN-GTT2-7 TSEN34 UBE2I UQCRC1 VEGFA VHL YBX1
Entrez ID		83943	3184
HPRD ID		07297	03206
Ensembl ID		ENSG00000184903	ENSG00000138668
Uniprot IDs		A4D0S9 Q96T52	A0A024RDB4 A0A024RDF4 A1LU37 Q14103
PDB IDs			1HD0 1HD1 1IQT 1WTB 1X0F 2Z5N 5IM0
Enriched GO Terms of Interacting Partners?
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