HNRNPD and FBXL15

Data Source:
BioGRID (two hybrid)

		HNRNPD	FBXL15
Description		heterogeneous nuclear ribonucleoprotein D	F-box and leucine rich repeat protein 15
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Synapse Ribonucleoprotein Complex	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Minor Groove Of Adenine-thymine-rich DNA Binding Chromatin Binding RNA Binding Protein Binding Transcription Factor Binding MRNA 3'-UTR AU-rich Region Binding Telomeric DNA Binding Histone Deacetylase Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Liver Development Regulation Of Transcription, DNA-templated RNA Processing RNA Catabolic Process Regulation Of Gene Expression RNA Metabolic Process Cerebellum Development Regulation Of Telomere Maintenance Regulation Of Circadian Rhythm Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Response To Calcium Ion Response To Electrical Stimulus 3'-UTR-mediated MRNA Destabilization Cellular Response To Amino Acid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Nitric Oxide Circadian Regulation Of Translation Response To Rapamycin Positive Regulation Of Telomere Capping Response To Sodium Phosphate Cellular Response To Putrescine Positive Regulation Of Telomerase RNA Reverse Transcriptase Activity Hepatocyte Dedifferentiation	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination Dorsal/ventral Pattern Formation Protein Ubiquitination Bone Mineralization Positive Regulation Of BMP Signaling Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Artenimol
Diseases
GWAS		Chronotype ( 30696823) Coronary artery disease ( 32469254 33020668) Morning person ( 30696823) Refractive error ( 32231278)	Prostate cancer ( 23535732) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		87 interacting genes: ABCC10 ACTB ADGRE5 ARF4 B3GAT3 BCL2 BET1L BRCA1 C1QBP CAPN1 CD81 CINP COG7 COL18A1 CSDE1 CTSB CUTA DGCR2 DHX30 DMAC1 EEF2 ERG ESR1 EXOSC4 FBXL15 FLNA GSK3B GTF3C3 GTSE1 GUK1 HBZ HDAC1 HIRA HMGA1 HNRNPF HNRNPH3 HSPA4 HSPB1 HSPB2 IGF2BP2 IL7R IMMP2L IMMT ING4 LDHA LSM5 MAP2K1 MAPK6 MEOX2 MPP1 MTA2 NTMT1 P4HB PABPC1 PCBP1 PCBP2 PCSK7 PDLIM7 PEX10 PPOX PRDX3 PRKACA PTBP2 PYCR1 RALY RPSA SAFB SDF2 SEPTIN9 SF3B4 SFN SHISA5 SLC27A5 SLC3A2 SNAPC4 SNRPC SREK1 SUMO4 SYNCRIP TNPO1 TRN-GTT2-7 TSEN34 UBE2I UQCRC1 VEGFA VHL YBX1	6 interacting genes: CSNK2B DELEC1 HNRNPD RORC SMURF1 UBC
Entrez ID		3184	79176
HPRD ID		03206	18876
Ensembl ID		ENSG00000138668	ENSG00000107872
Uniprot IDs		A0A024RDB4 A0A024RDF4 A1LU37 Q14103	Q9H469
PDB IDs		1HD0 1HD1 1IQT 1WTB 1X0F 2Z5N 5IM0
Enriched GO Terms of Interacting Partners?
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