KRTAP17-1 and WNT11

Data Source:
BioGRID (two hybrid)

		KRTAP17-1	WNT11
Description		keratin associated protein 17-1	Wnt family member 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Region Extracellular Space Cytoplasm Extracellular Matrix
	Molecular Function	Protein Binding	GTPase Activator Activity Frizzled Binding Cytokine Activity Protein Binding Protein Kinase Activator Activity
	Biological Process	Keratinization	Osteoblast Differentiation Epithelial To Mesenchymal Transition Primary Heart Field Specification Secondary Heart Field Specification Outflow Tract Morphogenesis Atrial Septum Development Planar Cell Polarity Pathway Involved In Axis Elongation Protein Phosphorylation Wnt Signaling Pathway, Calcium Modulating Pathway Positive Regulation Of Gene Expression Wnt Signaling Pathway Neuron Differentiation Bone Mineralization Negative Regulation Of Cell Growth Adrenal Gland Development Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Response To Nutrient Levels Activation Of Protein Kinase Activity Positive Regulation Of Transforming Growth Factor Beta2 Production Protein Localization To Cell Surface Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Cell Fate Commitment Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Paraxial Mesoderm Formation Notochord Morphogenesis Embryonic Skeletal System Development Artery Morphogenesis Positive Regulation Of Stress Fiber Assembly Convergent Extension Involved In Axis Elongation Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Cloacal Septation Ventricular Septum Morphogenesis Lung-associated Mesenchyme Development Negative Regulation Of Cell Death Ureteric Bud Morphogenesis Planar Cell Polarity Pathway Involved In Gastrula Mediolateral Intercalation Negative Regulation Of Cartilage Development Somite Development Neuroendocrine Cell Differentiation Secondary Palate Development Bicellular Tight Junction Assembly Cellular Response To Mechanical Stimulus Cellular Response To Retinoic Acid Mesonephric Duct Development Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Protein Kinase C Signaling Positive Regulation Of Heart Induction By Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Fibroblast Growth Factor Production
Pathways		Keratinization	WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors) Ca2+ pathway Ca2+ pathway PCP/CE pathway PCP/CE pathway
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Platelet count ( 32888494) Plateletcrit ( 32888494) PR interval ( 30046033 32439900 20062060)
Interacting Genes		47 interacting genes: CATSPER1 CELF5 CNNM3 CXCL16 DOCK2 GLP1R GNE HOXB9 HPCAL1 ITGB4 KRTAP10-8 KRTAP4-11 KRTAP4-4 KRTAP5-11 KRTAP5-6 KRTAP9-2 KRTAP9-8 LCE1B LCE1E LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE4A MRGBP MT1B MT1M NMU OTX1 PRKAB2 PRM2 SHFL SPDYE2 SPDYE2B THAP7 TLE5 VASN WNT11 YY1 ZBTB25 ZDHHC1 ZNF101 ZNF575 ZNF578 ZNF696	17 interacting genes: CCNDBP1 CYSRT1 FUCA2 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP9-3 MDFI RASSF10
Entrez ID		83902	7481
HPRD ID		13935	04741
Ensembl ID		ENSG00000186860	ENSG00000085741
Uniprot IDs		Q9BYP8	O96014
PDB IDs
Enriched GO Terms of Interacting Partners?
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