WNT11 and RASSF10

Data Source:
BioGRID (two hybrid)

		WNT11	RASSF10
Description		Wnt family member 11	Ras association domain family member 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Extracellular Matrix	Spindle Pole Microtubule Organizing Center Cytosol
	Molecular Function	GTPase Activator Activity Frizzled Binding Cytokine Activity Protein Binding Protein Kinase Activator Activity	Protein Binding
	Biological Process	Osteoblast Differentiation Epithelial To Mesenchymal Transition Primary Heart Field Specification Secondary Heart Field Specification Outflow Tract Morphogenesis Atrial Septum Development Planar Cell Polarity Pathway Involved In Axis Elongation Protein Phosphorylation Wnt Signaling Pathway, Calcium Modulating Pathway Positive Regulation Of Gene Expression Wnt Signaling Pathway Neuron Differentiation Bone Mineralization Negative Regulation Of Cell Growth Adrenal Gland Development Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Response To Nutrient Levels Activation Of Protein Kinase Activity Positive Regulation Of Transforming Growth Factor Beta2 Production Protein Localization To Cell Surface Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Cell Fate Commitment Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Paraxial Mesoderm Formation Notochord Morphogenesis Embryonic Skeletal System Development Artery Morphogenesis Positive Regulation Of Stress Fiber Assembly Convergent Extension Involved In Axis Elongation Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Cloacal Septation Ventricular Septum Morphogenesis Lung-associated Mesenchyme Development Negative Regulation Of Cell Death Ureteric Bud Morphogenesis Planar Cell Polarity Pathway Involved In Gastrula Mediolateral Intercalation Negative Regulation Of Cartilage Development Somite Development Neuroendocrine Cell Differentiation Secondary Palate Development Bicellular Tight Junction Assembly Cellular Response To Mechanical Stimulus Cellular Response To Retinoic Acid Mesonephric Duct Development Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Protein Kinase C Signaling Positive Regulation Of Heart Induction By Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Fibroblast Growth Factor Production	Signal Transduction Positive Regulation Of Neurogenesis Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors) Ca2+ pathway Ca2+ pathway PCP/CE pathway PCP/CE pathway
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Platelet count ( 32888494) Plateletcrit ( 32888494) PR interval ( 30046033 32439900 20062060)	Coronary artery disease ( 32469254) Empathy quotient ( 29527006) Obesity-related traits ( 23251661)
Interacting Genes		17 interacting genes: CCNDBP1 CYSRT1 FUCA2 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP9-3 MDFI RASSF10	23 interacting genes: ATP6V1E2 CBY1 CCDC116 CCDC183 CEP57 CEP70 EGFL7 EIF1AD FAM110A FAM171A1 GADD45G GNG13 GOLGA6L9 LDOC1 MAGEA6 NXT2 SMG9 SMU1 TEAD4 TNNI3 TP53BP2 TRIM54 WNT11
Entrez ID		7481	644943
HPRD ID		04741	19177
Ensembl ID		ENSG00000085741	ENSG00000189431
Uniprot IDs		O96014	A6NK89
PDB IDs
Enriched GO Terms of Interacting Partners?
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