Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CASP6 and CHD3
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CASP6
CHD3
Description
caspase 6
chromodomain helicase DNA binding protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Centrosome
NuRD Complex
PML Body
Centriolar Satellite
Molecular Function
Cysteine-type Endopeptidase Activity
Protein Binding
Cysteine-type Peptidase Activity
Identical Protein Binding
Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA Helicase Activity
RNA Binding
Helicase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
ATPase Activity
Double-stranded DNA Helicase Activity
Nucleosome-dependent ATPase Activity
Biological Process
Proteolysis
Apoptotic Process
Epithelial Cell Differentiation
Regulation Of Apoptotic Process
Cellular Response To Staurosporine
Execution Phase Of Apoptosis
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Assembly Or Disassembly
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Spindle Organization
Centrosome Cycle
DNA Duplex Unwinding
ATP-dependent Chromatin Remodeling
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Apoptotic cleavage of cellular proteins
Caspase-mediated cleavage of cytoskeletal proteins
Breakdown of the nuclear lamina
TP53 Regulates Transcription of Caspase Activators and Caspases
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
SUMOylation of chromatin organization proteins
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Risk-taking tendency (4-domain principal component model) (
30643258
)
Ischemic stroke (
26089329
)
Macular thickness (
30535121
)
Prostate cancer (
29892016
)
Refractive error (
32231278
)
Stroke (
26089329
)
Interacting Genes
42 interacting genes:
APP
CASP10
CASP3
CASP8
CFLAR
CHD3
COPS6
DSP
EIF2S1
HTT
IKBKG
KRT18
LMNA
LMNB1
LNX1
MAPK6
MAPT
NEDD4
NTAQ1
NUAK1
PCYT1A
PIN1
PKIA
PPL
PRKAB2
PRKCZ
PSEN1
PSEN2
PSME3
RB1
SATB1
SP1
SRF
SRP72
STUB1
TAB1
TFAP2A
TOP1
TRAF1
UBE4A
UBE4B
VIM
96 interacting genes:
ACTR1B
ADH5
AIMP2
ATP5IF1
BARD1
BCL6
BHLHE40
C4orf17
CASP6
CASP8
CPE
CRCT1
CREB1
CREBBP
CSTF2
CTBP1
CTTN
ENTR1
FABP4
FBP2
FUBP1
GADD45A
GIT1
GPS2
GSK3B
H3C1
HABP4
HSD17B10
HSPH1
HTT
IK
IKZF1
IKZF3
IMMT
IVNS1ABP
KIF15
KPNA2
KPNB1
LRIF1
LUC7L2
MAFG
MAN2A2
MX1
MYB
NEFL
NR1H2
NR4A1
PAICS
PCMT1
PIAS4
PLK4
PRG2
PRPF40A
PSME1
PTN
PTPRS
PUF60
RAD51
RETREG2
RGS2
RIF1
RPL29
SAFB
SAT1
SATB1
SERBP1
SERF2
SGSM2
SIRT6
SKIL
SLC27A6
SPOP
SRRT
SUMO1
SUMO2
TAL1
TCERG1
THOC7
TNFRSF14
TNNT1
TP53
TP73
TRIM28
TRIM54
TSC22D1
TSPAN6
TTR
TXNDC9
UBA3
UBC
UBE2I
UROD
VIM
XRCC4
YAE1
ZHX1
Entrez ID
839
1107
HPRD ID
03321
09071
Ensembl ID
ENSG00000138794
ENSG00000170004
Uniprot IDs
P55212
B3KWV4
Q12873
Q2TAZ1
PDB IDs
1MI9
2WDP
3K7E
3NKF
3NR2
3OD5
3P45
3P4U
3QNW
3S70
3S8E
3V6L
3V6M
4EJF
4FXO
4HVA
4IYR
4N5D
4N6G
4N7J
4N7M
4NBK
4NBL
4NBN
6DEU
6DEV
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?