KCTD10 and KCTD13

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		KCTD10	KCTD13
Description		potassium channel tetramerization domain containing 10	potassium channel tetramerization domain containing 13
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex	Nucleoplasm Nuclear Body Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Notch Binding Protein Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein Domain Specific Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Homooligomerization	Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Synaptic Transmission Protein Homooligomerization Neural Precursor Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668) Fish- and plant-related diet ( 32066663) HDL cholesterol ( 20864672) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Hand grip strength ( 29691431) Menarche (age at onset) ( 25231870) Schizophrenia ( 28991256 25056061 29483656 30285260) Urinary sodium excretion ( 31409800)
Interacting Genes		8 interacting genes: CUL3 DVL3 ITSN2 KCTD13 NTAQ1 TCEA2 TEX11 TNFAIP1	21 interacting genes: ADRB2 ARMC7 CDC37 CRK CUL3 EXOSC5 GORASP2 KAT7 KCTD10 LNX1 NTAQ1 NUDT18 PCNA POLD2 POLR1C PPARG PSMA1 RHOA TNFAIP1 VTA1 ZMYND19
Entrez ID		83892	253980
HPRD ID		13762	12339
Ensembl ID		ENSG00000110906	ENSG00000174943
Uniprot IDs		A0A024RBJ2 Q9H3F6	A0A3B3IS45 Q8WZ19
PDB IDs		5FTA	4UIJ
Enriched GO Terms of Interacting Partners?
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