L3MBTL2 and RBAK

Data Source:
BioGRID (two hybrid)

		L3MBTL2	RBAK
Description		L3MBTL histone methyl-lysine binding protein 2	RB associated KRAB zinc finger
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding
	Biological Process	Chromatin Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated
Pathways		SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Lamb consumption ( 32066663) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		49 interacting genes: AMOTL2 BEND7 BHLHB9 BIVM CARD9 CCDC106 CCDC33 CEP76 EFHC2 EIF4ENIF1 FAM217B GAS8 GKAP1 GOLGA2 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829	28 interacting genes: AQP1 AR BYSL CARD9 CIB3 CRACR2A EFEMP2 EIF1AD FGF12 GAS8 L3MBTL2 LMO4 LNX1 MAGOHB NEK6 PRKG1 PRPF31 RB1 SCNM1 SLC25A10 TCAF1 TNS2 TRIM41 TSGA10 TXK ZNF121 ZNF330 ZNF648
Entrez ID		83746	57786
HPRD ID		13954	16296
Ensembl ID		ENSG00000100395	ENSG00000146587
Uniprot IDs		A0A0S2Z5X6 Q969R5	Q9NYW8
PDB IDs		2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
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