L3MBTL2 and STAM2

L3MBTL2

STAM2

Description L3MBTL histone methyl-lysine binding protein 2 signal transducing adaptor molecule 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Crohn's disease ( 26192919)
  • Depression ( 29700475)
  • General risk tolerance (MTAG) ( 30643258)
  • Inflammatory bowel disease ( 26192919)
  • Lamb consumption ( 32066663)
  • Major depressive disorder ( 27479909)
  • Neuroticism ( 29255261 27918536)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Adverse response to chemotherapy in breast cancer (alopecia) ( 24025145)
  • Metabolic syndrome ( 31170924)
  • Pulse pressure ( 30224653)
Interacting Genes 49 interacting genes: AMOTL2 BEND7 BHLHB9 BIVM CARD9 CCDC106 CCDC33 CEP76 EFHC2 EIF4ENIF1 FAM217B GAS8 GKAP1 GOLGA2 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829 39 interacting genes: ABI2 ARRDC3 ATXN1 CBX5 CDC7 DAZAP2 EGFR EPS15 FAM189A2 HGS ITCH JAK1 JAK2 JAK3 KLHL42 L3MBTL2 LCP2 LITAF MAP3K1 PHF10 PLEKHB2 PTPN1 RNF11 SH2D4A STAMBP TIMM8A TYK2 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBQLN1 UBQLN2 UBQLN4 USP8 VPS37C XRN1 ZC3H10
Entrez ID 83746 10254
HPRD ID 13954 05876
Ensembl ID ENSG00000100395 ENSG00000115145
Uniprot IDs A0A0S2Z5X6 Q969R5 O75886
PDB IDs 2W0T 3CEY 3F70 1X2Q 1X5B 2L0T 5CRV 5IXF
Enriched GO Terms of Interacting Partners?
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