H4C7 and FGF14

Data Source:
BioGRID (two hybrid)

		H4C7	FGF14
Description		H4 clustered histone 7	fibroblast growth factor 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus	Extracellular Region Nucleus Cytoplasm
	Molecular Function	Molecular_function DNA Binding Protein Binding Protein Heterodimerization Activity	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity
	Biological Process	Nucleosome Assembly Biological_process	Signal Transduction Cell-cell Signaling Nervous System Development Regulation Of Synaptic Plasticity Regulation Of Postsynaptic Membrane Potential Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Voltage-gated Sodium Channel Activity
Pathways			Phase 0 - rapid depolarisation
Drugs
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Bone mineral density (hip) ( 30172743) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		8 interacting genes: AGTRAP APOC1 CIDEB FGF14 FKBP7 MAIP1 RHBDD2 TMED8	13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA
Entrez ID		8369	2259
HPRD ID		11806	03305
Ensembl ID		ENSG00000275663	ENSG00000102466
Uniprot IDs		Q99525	Q92915
PDB IDs
Enriched GO Terms of Interacting Partners?
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