CHAF1B and CBR1

Data Source:
BioGRID (biochemical)

		CHAF1B	CBR1
Description		chromatin assembly factor 1 subunit B	carbonyl reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex	Cytosol Extracellular Exosome Extracellular Vesicle
	Molecular Function	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding	Carbonyl Reductase (NADPH) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity Prostaglandin-E2 9-reductase Activity
	Biological Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly	Drug Metabolic Process Cyclooxygenase Pathway Epithelial Cell Differentiation Vitamin K Metabolic Process
Pathways			Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs			Rutin Resveratrol Heptaethylene glycol 2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 Quercetin 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol Curcumin Curcumin sulfate
Diseases
GWAS		Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)	Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497)
Interacting Genes		10 interacting genes: APP ASF1A ASF1B CDK1 CDK2 CHAF1A H3-4 H3C6 RBBP4 SUMO2	7 interacting genes: AGTR1 ERBB2 ERCC8 HTR2B PTPRF UBC VHL
Entrez ID		8208	873
HPRD ID		03147	00267
Ensembl ID		ENSG00000159259	ENSG00000159228
Uniprot IDs		Q13112	A0A384NL53 P16152
PDB IDs			1WMA 2PFG 3BHI 3BHJ 3BHM 4Z3D
Enriched GO Terms of Interacting Partners?
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