MKKS and ZBED1

Data Source:
BioGRID (two hybrid)

		MKKS	ZBED1
Description		McKusick-Kaufman syndrome	zinc finger BED-type containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Motile Cilium Kinociliary Basal Body	Chromatin Nucleus Nucleoplasm Centrosome PML Body Nuclear Membrane
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding ATP Binding Unfolded Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity SUMO Ligase Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Heart Looping Protein Folding Spermatid Development Determination Of Left/right Symmetry Heart Development Visual Perception Sensory Perception Of Smell Gonad Development Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Negative Regulation Of Actin Filament Polymerization Melanosome Transport Developmental Process Negative Regulation Of GTPase Activity Social Behavior Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Positive Regulation Of Multicellular Organism Growth Vasodilation Fat Cell Differentiation Photoreceptor Cell Maintenance Negative Regulation Of Blood Pressure Intracellular Transport Brain Morphogenesis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Chaperone-mediated Protein Complex Assembly Cartilage Development Regulation Of Stress Fiber Assembly Pigment Granule Aggregation In Cell Center Convergent Extension Involved In Gastrulation Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Face Development Non-motile Cilium Assembly	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Viral Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Protein Autosumoylation
Pathways		BBSome-mediated cargo-targeting to cilium	SUMOylation of chromatin organization proteins
Drugs
Diseases		46,XX disorders of sex development (Other), including: Mullerian aplasia and hyperandrogenism; McKusick-Kaufman syndrome Bardet-Biedl syndrome (BBS)
GWAS
Interacting Genes		4 interacting genes: APP CDR2 PTN ZBED1	55 interacting genes: AMOTL2 ATRX C1orf109 CCDC13 CDC37 CTNNAL1 DGCR6 EFHC1 FABP4 FAM124B FANCG FNDC11 GGACT GORASP2 GPN1 GPSM1 KDM1A KIFC3 KLHL40 LCN2 LNX1 LRRC20 MAD2L2 MAGEB2 MKKS MLH1 MPST MYO15B NCDN NIF3L1 NIP7 NTAQ1 NUDT18 PAX6 PIAS2 PICK1 POLE2 POLR1C PRKAA1 PRKAR1A PSAP RENBP RIN1 SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2 TRAPPC2B TRIML2 TTC23 TTR UBE2I UCHL5 USP2
Entrez ID		8195	9189
HPRD ID		05356	02170
Ensembl ID		ENSG00000125863	ENSG00000214717
Uniprot IDs		B7Z3W9 Q9NPJ1	A0A024RBU4 O96006
PDB IDs			2CT5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?