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MKKS and CDR2
Data Source:
BioGRID
(two hybrid)
MKKS
CDR2
Description
McKusick-Kaufman syndrome
cerebellar degeneration related protein 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cytosol
Motile Cilium
Kinociliary Basal Body
Molecular Function
RNA Polymerase II Repressing Transcription Factor Binding
Protein Binding
ATP Binding
Unfolded Protein Binding
Molecular_function
Protein Binding
Biological Process
Heart Looping
Protein Folding
Spermatid Development
Determination Of Left/right Symmetry
Heart Development
Visual Perception
Sensory Perception Of Smell
Gonad Development
Negative Regulation Of Gene Expression
Artery Smooth Muscle Contraction
Striatum Development
Hippocampus Development
Cerebral Cortex Development
Negative Regulation Of Actin Filament Polymerization
Melanosome Transport
Developmental Process
Negative Regulation Of GTPase Activity
Social Behavior
Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway
Positive Regulation Of Multicellular Organism Growth
Vasodilation
Fat Cell Differentiation
Photoreceptor Cell Maintenance
Negative Regulation Of Blood Pressure
Intracellular Transport
Brain Morphogenesis
Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound
Chaperone-mediated Protein Complex Assembly
Cartilage Development
Regulation Of Stress Fiber Assembly
Pigment Granule Aggregation In Cell Center
Convergent Extension Involved In Gastrulation
Cilium Assembly
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Face Development
Non-motile Cilium Assembly
Pathways
BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
46,XX disorders of sex development (Other), including: Mullerian aplasia and hyperandrogenism; McKusick-Kaufman syndrome
Bardet-Biedl syndrome (BBS)
GWAS
Interacting Genes
4 interacting genes:
APP
CDR2
PTN
ZBED1
75 interacting genes:
AMOTL2
ANKRD36BP1
AQP1
ARNT2
BEX2
C1orf216
C2CD6
C4orf46
CCDC120
CCDC13
CCDC146
CCDC153
CCDC187
CCDC87
CCHCR1
CDC20
CDR2L
CEP57L1
CHIC2
COX5B
EIF4E2
ENKD1
FAM110A
FAM161A
FAM50B
FAM90A1
FZR1
GAS8
GEM
GMPPA
HAUS1
HDAC4
HGS
KANSL1
KIF5B
KIFC3
LENG1
LIN37
MICALL2
MKKS
MNS1
MORF4L2
MRPL28
NDN
NTAQ1
OAZ2
PKN1
PRKAA2
PRPF18
PSMA1
RCOR3
RSPH14
RUNX1T1
SCNM1
SH2D4A
SMARCD1
SMARCE1
TBC1D22B
TCHP
TEAD4
TEX28
TMCC2
TRIM23
TRIML2
TSGA10IP
TTC23
TTR
TXLNA
TXLNB
UBTFL1
ZGPAT
ZMAT2
ZNF250
ZNF35
ZNF417
Entrez ID
8195
1039
HPRD ID
05356
06681
Ensembl ID
ENSG00000125863
ENSG00000140743
Uniprot IDs
B7Z3W9
Q9NPJ1
Q01850
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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