CDR2 and LIN37

Data Source:
BioGRID (two hybrid)

		CDR2	LIN37
Description		cerebellar degeneration related protein 2	lin-37 DREAM MuvB core complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Transcription Repressor Complex Myb Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle
Pathways			Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)
Interacting Genes		75 interacting genes: AMOTL2 ANKRD36BP1 AQP1 ARNT2 BEX2 C1orf216 C2CD6 C4orf46 CCDC120 CCDC13 CCDC146 CCDC153 CCDC187 CCDC87 CCHCR1 CDC20 CDR2L CEP57L1 CHIC2 COX5B EIF4E2 ENKD1 FAM110A FAM161A FAM50B FAM90A1 FZR1 GAS8 GEM GMPPA HAUS1 HDAC4 HGS KANSL1 KIF5B KIFC3 LENG1 LIN37 MICALL2 MKKS MNS1 MORF4L2 MRPL28 NDN NTAQ1 OAZ2 PKN1 PRKAA2 PRPF18 PSMA1 RCOR3 RSPH14 RUNX1T1 SCNM1 SH2D4A SMARCD1 SMARCE1 TBC1D22B TCHP TEAD4 TEX28 TMCC2 TRIM23 TRIML2 TSGA10IP TTC23 TTR TXLNA TXLNB UBTFL1 ZGPAT ZMAT2 ZNF250 ZNF35 ZNF417	18 interacting genes: CCNDBP1 CDR2 CEP70 KIFC3 KRT31 KRT40 LZTS2 MAGEA6 MEOX2 PDE4DIP PNMA1 PSTPIP1 RBBP4 TEX11 TFIP11 TRAF1 TRIM54 ZNF76
Entrez ID		1039	55957
HPRD ID		06681	16872
Ensembl ID		ENSG00000140743	ENSG00000267796
Uniprot IDs		Q01850	Q96GY3
PDB IDs
Enriched GO Terms of Interacting Partners?
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