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KRTAP1-3 and PRKAB2
Data Source:
BioGRID
(two hybrid, two hybrid)
KRTAP1-3
PRKAB2
Description
keratin associated protein 1-3
protein kinase AMP-activated non-catalytic subunit beta 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Keratin Filament
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nucleotide-activated Protein Kinase Complex
Molecular Function
Structural Constituent Of Skin Epidermis
AMP-activated Protein Kinase Activity
Protein Binding
Protein Kinase Binding
Identical Protein Binding
Biological Process
Biological_process
Keratinization
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Carnitine Shuttle
Cell Cycle Arrest
Signal Transduction
Macroautophagy
Regulation Of Macroautophagy
Regulation Of Fatty Acid Biosynthetic Process
Regulation Of Catalytic Activity
Regulation Of Primary Metabolic Process
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Keratinization
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
AMPK inhibits chREBP transcriptional activation activity
Carnitine metabolism
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Diseases
GWAS
Interacting Genes
176 interacting genes:
ADAM12
AGA
ALDH3B1
ALPP
ATG9A
BCAM
BHLHE40
BMP7
BTC
C19orf25
C2orf68
CATSPER1
CELF5
CHIC2
CHRD
CHRNG
CLDN2
CMTM8
CNNM3
COA5
COL8A1
CRCT1
CREB5
CRH
CRY2
CTNNBIP1
CXCL16
CYHR1
CYP21A2
CYSRT1
DHRS1
DLGAP3
DMRT3
DOCK2
ECE1
FBXW5
GLP1R
GLRX3
GNE
GRAP2
GSTP1
HCK
HHEX
HHIPL1
HOXA1
HOXB9
HOXC8
HPCAL1
HSD3B7
IGSF8
IL10
IL16
INPP5D
INS
ITGB4
ITGB5
JOSD1
KLHL38
KPRP
KRTAP10-1
KRTAP10-11
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LONRF1
LRFN4
MAPKBP1
MOS
MTNR1A
MXD3
MXI1
MYPOP
NAXD
NECTIN2
NECTIN3
NID2
NMU
NPBWR2
NPDC1
NR1D2
NUFIP2
OLFM2
OTX1
P3H3
PDE9A
PDIA5
PHETA1
PHLDA1
PIGS
PLEKHN1
PRKAA2
PRKAB2
PRPF31
PSMA1
PTK7
PTPMT1
PVR
R3HDM2
RAMAC
RANBP3
RASD1
RPN1
RPS19BP1
SAPCD2
SDC3
SDCBP
SELENOM
SHFL
SLC13A5
SLC22A23
SLC23A1
SLC39A7
SLC43A2
SLC7A11
SMCP
SPINT1
SPRY1
STK16
SUSD6
TACSTD2
TCAF1
TFAP2D
TGFB1
THAP7
TNS2
UNC119
UTP23
UXT
VASN
VSTM4
WNT11
XCL2
YIPF3
YY1
ZDHHC1
ZNF330
ZNF414
ZNF417
ZNF440
ZNF446
ZNF497
ZNF587
ZNF696
ZNF764
ZNF786
ZNF837
170 interacting genes:
ABHD11
ADAMTSL4
ANAPC11
ARID5A
AUNIP
AVP
BANP
BEND5
BHLHB9
BLZF1
C11orf1
C19orf54
C2orf42
C3orf36
CALCOCO2
CASP2
CASP6
CCDC28B
CCDC33
CDC14B
CDSN
CDX4
CFP
CREB3L1
CRX
CSNK2B
CYSRT1
DAO
DDAH2
DDIT4L
DICER1
DOK3
DST
ELL2
EPM2A
ESM1
FDX1
FLNC
GATA1
GATAD2B
GCSAML
GET4
GOLGA2
GOLGA6L9
GORASP2
GRAPL
GRN
GSC2
IHO1
IKZF1
IKZF3
IL37
IRAK1BP1
KATNBL1
KCTD5
KHDC4
KLF15
KRBOX4
KRT31
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP3-3
KRTAP4-12
KRTAP4-2
KRTAP4-5
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LHX3
LRIF1
LZTS1
LZTS2
MAGED1
MAJIN
MDFI
MEOX2
METTL27
MORN3
NAB2
NEBL
NHLRC4
NUTM1
OXER1
PDE6G
PDE6H
PFDN5
PIAS2
PNMA1
PPP1R13B
PPP1R16A
PRDM14
PRKAA1
PRKAG1
PRKAG2
PSMD11
PSME3
PYGM
QKI
RAB3IP
RACK1
RBM48
RBPMS
REL
RHEBL1
RIMBP3
RNF144B
ROR2
RPH3AL
SAMD4A
SERTAD2
SMARCB1
SMUG1
SPRY1
SPRY2
SSC4D
SSX2IP
STX11
STX19
TADA2A
TASOR2
TCF12
TCF19
TCF4
TCF7L2
TGM7
TLE5
TNNI1
TP53
TP53BP2
TRAF1
TRAF2
TRIB3
TRIM10
TRIM14
TRIM35
TRIM42
TRIM54
TRIM55
TRIM63
TSR2
TTC23
UBXN11
USP54
VBP1
VPS28
WDR83
YPEL3
YY1AP1
ZBTB32
ZC2HC1C
ZFP90
ZMYND19
ZNF177
ZNF236
ZNF474
ZNF526
ZNF559-ZNF177
ZNF581
Entrez ID
81850
5565
HPRD ID
12305
04117
Ensembl ID
ENSG00000221880
ENSG00000131791
Uniprot IDs
Q8IUG1
O43741
PDB IDs
2F15
2V8Q
2V92
2V9J
2Y8L
2Y8Q
2YA3
4CFH
4EAI
4EAJ
4RER
4REW
6B2E
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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