POLR2M and UQCRQ

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLR2M	UQCRQ
Description		RNA polymerase II subunit M	ubiquinol-cytochrome c reductase complex III subunit VII
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GO Annotations	Cellular Component	Intracellular Anatomical Structure Nuclear Envelope RNA Polymerase II, Core Complex RNA Polymerase II, Holoenzyme Neuronal Cell Body	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Integral Component Of Membrane
	Molecular Function	DNA-directed 5'-3' RNA Polymerase Activity	Ubiquinol-cytochrome-c Reductase Activity
	Biological Process	RNA Biosynthetic Process Intracellular Signal Transduction Maintenance Of ER Location	Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Subthalamus Development Pons Development Cerebellar Purkinje Cell Layer Development Hippocampus Development Thalamus Development Hypothalamus Development Pyramidal Neuron Development Midbrain Development
Pathways			Respiratory electron transport
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Body mass index ( 28552196) Seasonality ( 25562672)	Asthma ( 31619474)
Interacting Genes		22 interacting genes: AHSP ANKHD1 APOD CEBPG CEP126 DAPK1 DGKZ HIGD1B LRRK1 LRRK2 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410	4 interacting genes: ERCC6 ERCC8 OPTN POLR2M
Entrez ID		81488	27089
HPRD ID		07575	17941
Ensembl ID		ENSG00000255529	ENSG00000164405
Uniprot IDs		P0CAP1 P0CAP2 Q6EEV4	O14949
PDB IDs		2KXS 6DRD	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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