IFT88 and SAP18

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		IFT88	SAP18
Description		intraflagellar transport 88	Sin3A associated protein 18
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Sperm Flagellum Ciliary Tip Ciliary Base Non-motile Cilium	Histone Deacetylase Complex Nucleus Nucleoplasm Cytosol Nuclear Body Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	Protein Binding Kinesin Binding	Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding
	Biological Process	Kidney Development Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Cilium Assembly Non-motile Cilium Assembly Regulation Of Autophagosome Assembly	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Coronary artery calcification ( 23870195) Dental caries ( 23064961) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		10 interacting genes: CAPN7 CCDC120 EEF2KMT EML2 FBXO7 ITPKB MSRB1 PRRC2A RPGR SMARCE1	15 interacting genes: DEF6 ERBB3 HDAC1 IKZF1 INCA1 NOL12 NTAQ1 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3 TSC22D2
Entrez ID		8100	10284
HPRD ID		09000	04256
Ensembl ID		ENSG00000032742	ENSG00000150459
Uniprot IDs		A0A140VJL7 B3KX42 Q13099	O00422
PDB IDs			2HDE
Enriched GO Terms of Interacting Partners?
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