IFT88 and RPGR

Data Source:
HPRD (in vivo)

		IFT88	RPGR
Description		intraflagellar transport 88	retinitis pigmentosa GTPase regulator
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Sperm Flagellum Ciliary Tip Ciliary Base Non-motile Cilium	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum
	Molecular Function	Protein Binding Kinesin Binding	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Kidney Development Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Cilium Assembly Non-motile Cilium Assembly Regulation Of Autophagosome Assembly	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases			Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)
GWAS		Coronary artery calcification ( 23870195) Dental caries ( 23064961) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		10 interacting genes: CAPN7 CCDC120 EEF2KMT EML2 FBXO7 ITPKB MSRB1 PRRC2A RPGR SMARCE1	14 interacting genes: DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE
Entrez ID		8100	6103
HPRD ID		09000	02425
Ensembl ID		ENSG00000032742	ENSG00000156313
Uniprot IDs		A0A140VJL7 B3KX42 Q13099	Q92834
PDB IDs			4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?