YEATS4 and FRMD4A

Data Source:
BioGRID (two hybrid)

		YEATS4	FRMD4A
Description		YEATS domain containing 4	FERM domain containing 4A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex	Cytoplasm Cytoskeleton Adherens Junction Bicellular Tight Junction
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding	Protein-macromolecule Adaptor Activity
	Biological Process	Mitotic Cell Cycle Cytoskeleton Organization Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Protein Secretion Positive Regulation Of Protein Secretion Establishment Of Epithelial Cell Polarity
Pathways		HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors
Drugs
Diseases
GWAS		Complete remission in asthma ( 29786918) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Height ( 31562340 18391951) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiouness ( 29559929) Thyroid stimulating hormone levels ( 32769997)	Adiponectin levels ( 26299439) Alcohol consumption (max-drinks) ( 29460428) Alzheimer's disease ( 22430674) Chronic obstructive pulmonary disease ( 32222710) Craniofacial microsomia ( 26853712) Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hematocrit ( 32888494) Hemoglobin ( 32888494) Knee osteoarthritis ( 27696742) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Obstetric antiphospholipid syndrome ( 28424481) Rapid automised naming of digits ( 30741946) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) RR interval (heart rate) ( 20031603) Takayasu arteritis ( 25604533)
Interacting Genes		17 interacting genes: ANKK1 CEP162 FRMD4A GTF2F2 H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B TPM1 TRIM54	2 interacting genes: TRAF3IP1 YEATS4
Entrez ID		8089	55691
HPRD ID		03666	13553
Ensembl ID		ENSG00000127337	ENSG00000151474
Uniprot IDs		F8W0J4 O95619	Q9NW91 Q9P2Q2
PDB IDs		5VNA 5VNB 5XTZ 5Y8V
Enriched GO Terms of Interacting Partners?
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