FRMD4A and YEATS4

Data Source:
BioGRID (two hybrid)

		FRMD4A	YEATS4
Description		FERM domain containing 4A	YEATS domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Adherens Junction Bicellular Tight Junction	Nucleus Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein-macromolecule Adaptor Activity	Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding
	Biological Process	Negative Regulation Of Protein Secretion Positive Regulation Of Protein Secretion Establishment Of Epithelial Cell Polarity	Mitotic Cell Cycle Cytoskeleton Organization Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors
Drugs
Diseases
GWAS		Adiponectin levels ( 26299439) Alcohol consumption (max-drinks) ( 29460428) Alzheimer's disease ( 22430674) Chronic obstructive pulmonary disease ( 32222710) Craniofacial microsomia ( 26853712) Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hematocrit ( 32888494) Hemoglobin ( 32888494) Knee osteoarthritis ( 27696742) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Obstetric antiphospholipid syndrome ( 28424481) Rapid automised naming of digits ( 30741946) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) RR interval (heart rate) ( 20031603) Takayasu arteritis ( 25604533)	Complete remission in asthma ( 29786918) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Height ( 31562340 18391951) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiouness ( 29559929) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		2 interacting genes: TRAF3IP1 YEATS4	17 interacting genes: ANKK1 CEP162 FRMD4A GTF2F2 H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B TPM1 TRIM54
Entrez ID		55691	8089
HPRD ID		13553	03666
Ensembl ID		ENSG00000151474	ENSG00000127337
Uniprot IDs		Q9NW91 Q9P2Q2	F8W0J4 O95619
PDB IDs			5VNA 5VNB 5XTZ 5Y8V
Enriched GO Terms of Interacting Partners?
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